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33823

Supelco

Decoquinate

VETRANAL®, analytical standard

Synonym(s):

Ethyl 6-decyloxy-7-ethoxy-4-hydroxy-3-quinolinecarboxylate

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About This Item

Empirical Formula (Hill Notation):
C24H35NO5
CAS Number:
Molecular Weight:
417.54
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)

format

neat

SMILES string

CCCCCCCCCCOc1cc2c(O)c(cnc2cc1OCC)C(=O)OCC

InChI

1S/C24H35NO5/c1-4-7-8-9-10-11-12-13-14-30-21-15-18-20(16-22(21)28-5-2)25-17-19(23(18)26)24(27)29-6-3/h15-17H,4-14H2,1-3H3,(H,25,26)

InChI key

JHAYEQICABJSTP-UHFFFAOYSA-N

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General description

Decoquinate is a quinolone coccidiostat used in poultry, to retard the growth of coccidian parasites and can also show activity against Plasmodium falciparum parasite, which causes malaria in humans.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

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Pricing

Hazard Statements

Precautionary Statements

Hazard Classifications

Aquatic Chronic 4

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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D S Lindsay et al.
Veterinary parasitology, 68(1-2), 35-40 (1997-01-01)
Neospora caninum is a major cause of abortion in dairy cattle in the United States and other countries. Abortions and neonatal mortality also occur in other ruminant species. Decoquinate is an anticoccidial that is approved for use in cattle and
Medicating feeds for early lambing ewes.
Neville Suttle
The Veterinary record, 170(6), 161-161 (2012-02-15)
F C Guo et al.
Veterinary parasitology, 147(3-4), 239-245 (2007-05-09)
The efficacy of decoquinate against Eimeria infections in broiler chickens was evaluated using two drug sensitive laboratory strains of Eimeria tenella and 20 field isolates of Eimeria spp. collected from farms in China where various anticoccidials (including maduramicin) had been
Tae-Gyu Nam et al.
ACS chemical biology, 6(11), 1214-1222 (2011-08-27)
Decoquinate has single-digit nanomolar activity against in vitro blood stage Plasmodium falciparum parasites, the causative agent of human malaria. In vitro evolution of decoquinate-resistant parasites and subsequent comparative genomic analysis to the drug-sensitive parental strain revealed resistance was conferred by
Supply of Deccox 25 Individual Treatment Packs.
Janis McDonald
The Veterinary record, 164(12), 378-378 (2009-03-24)

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