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318604

Sigma-Aldrich

Ammonium chloride-ammonium hydroxide buffer solution

in H2O

Synonym(s):

Ammonium Buffer Solution

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About This Item

MDL number:
UNSPSC Code:
12161705
PubChem Substance ID:
NACRES:
NA.21

form

liquid

Quality Level

composition

NH4Cl, 1 wt. %
NH4OH, 4 wt. % (pH 10 to 11)

concentration

in H2O

pH

10-11

density

0.99 g/mL at 25 °C

SMILES string

N.N.O.Cl

InChI

1S/ClH.2H3N.H2O/h1H;2*1H3;1H2

InChI key

XEXFVRMLYUDDJY-UHFFFAOYSA-N

Application

Ammonium chloride-ammonium hydroxide buffer solution may be used to crystallize proteins.

Biochem/physiol Actions

Ammonium chloride is the salt component of ammonium chloride-ammonium hydroxide buffer system that completely inhibits the BVDV infection of MDBK cells when present at a concentration of 50 mM . Viruses treated with ammonium chloride (NH4Cl) results in loss of infectivity because it neutralizes the pH of endosome. Hence, viruses with low pH-dependent fusion activity became incapable to fuse their envelope with endosomal membrane.

Pictograms

CorrosionEnvironment

Signal Word

Danger

Hazard Statements

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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