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Key Documents

1.01995

Supelco

tert-Butyl methyl ether

for gas chromatography ECD and FID SupraSolv®

Synonym(s):

tert-Butyl methyl ether, MTBE, MTB, 2-Methoxy-2-methylpropane, Methyl tert-butyl ether

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About This Item

Linear Formula:
(CH3)3COCH3
CAS Number:
Molecular Weight:
88.15
MDL number:
UNSPSC Code:
12191502
EC Index Number:
216-653-1
NACRES:
NA.03

vapor pressure

268 hPa ( 20 °C)

Quality Level

product line

SupraSolv®

Assay

≥99.8% (GC)

form

liquid

autoignition temp.

460 °C

potency

>2000 mg/kg LD50, oral (Rat)
>2000 mg/kg LD50, skin (Rabbit)

expl. lim.

1.5-8.5 % (v/v)

technique(s)

gas chromatography (GC): suitable

kinematic viscosity

0.409 cSt(40 °C)

bp

55.3 °C/1013 hPa

mp

-108.6 °C

transition temp

flash point -28 °C

density

0.74 g/cm3 at 20 °C

storage temp.

2-30°C

InChI

1S/C5H12O/c1-5(2,3)6-4/h1-4H3

InChI key

BZLVMXJERCGZMT-UHFFFAOYSA-N

General description

SupraSolv ECD and FID is specially developed for gas chromatography in combination with ECD (Electron Capture Detetor) and FID (Flame Ionization detector). SupraSolv solvents offer the largest specified retention time range, a clear baseline and a minimal signal-to-noise ratio leading to reliable and reproducible analysis results.

Application


  • Lipase-catalyzed kinetic resolution of novel antitubercular benzoxazole derivatives.: This study used tert-Butyl methyl ether in the lipase-catalyzed kinetic resolution of benzoxazole derivatives, demonstrating its application in the synthesis of enantiomerically pure compounds important for medicinal chemistry (Łukowska-Chojnacka et al., 2018).

  • A chemoenzymatic approach to the synthesis of enantiomerically pure (S)-3-hydroxy-gamma-butyrolactone.: The research developed a chemoenzymatic method using tert-Butyl methyl ether for synthesizing enantiomerically pure compounds, highlighting its utility in producing important chiral building blocks for pharmaceuticals (Lee et al., 2008).

  • Determination of roxatidine in human plasma by liquid chromatography/electrospray mass spectrometry and application to a clinical pharmacokinetic study.: This study demonstrated the use of tert-Butyl methyl ether in sample preparation for the analysis of roxatidine in human plasma, emphasizing its role in pharmacokinetic studies (Shin et al., 2007).

  • Analysis of coumarin 7-hydroxylation activity of cytochrome P450 2A6 using random mutagenesis.: This paper used tert-Butyl methyl ether in the study of enzyme activity, showing its effectiveness in biochemical assays involving cytochrome P450 enzymes (Kim et al., 2005).

  • Comparative fatty acid selectivity of lipases in esterification reactions with glycerol and diol analogues in organic media.: The research employed tert-Butyl methyl ether to investigate lipase selectivity in esterification reactions, illustrating its importance in biocatalysis and industrial applications of enzymatic processes (Lee & Parkin, 2000).

Other Notes

Explore various lab safety accessories and equipment for safe handling of solvents to increase your safety level from the first usage.

Legal Information

SUPRASOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Product No.
Description
Pricing

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Statements

Hazard Classifications

Flam. Liq. 2 - Skin Irrit. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

-18.4 °F - closed cup

Flash Point(C)

-28 °C - closed cup


Certificates of Analysis (COA)

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