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Key Documents

190001C

Avanti

Yeast Extract Polar

Avanti Research™ - A Croda Brand

Synonym(s):

Yeast Extract Polar, Yeast Polar Lipid Extract (S. cerevisiae)

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About This Item

UNSPSC Code:
12352211
NACRES:
NA.25

form

chloroform solution

packaging

pkg of 1 × 4 mL (190001C-100mg)
pkg of 5 × 4 mL (190001C-500mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand

concentration

25 mg/mL (190001C-100mg)
25 mg/mL (190001C-500mg)

lipid type

lipid extracts

shipped in

dry ice

storage temp.

−20°C

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General description

Polar Lipid Extract is derived from the total lipid extract by precipitation with acetone followed by extraction of the acetone insoluble material with diethyl ether.
Yeast is rich in sphingolipids. The apolar lipids from yeast separate out first during chloroform/methanol extraction. The aqueous phase contains polar lipids. A total of 162 lipids pertaining to 21 lipid classes have been identified in yeast. Phosphatidylinositol comprises the major component of yeast lipid accounting to 17% to 30%.

Application

Yeast Extract Polar has been used as a component of liposome for proteoliposomes preparation.

Biochem/physiol Actions

Yeast lipids serve as model membranes for understanding the lipid raft forming mechanisms. These lipids have the potential to self-organize. The fatty acid composition of polar lipids in yeast are modulated in response to acid stress. The total lipids from yeast are useful in understanding lipid metabolism.

Packaging

5 mL Clear Glass Sealed Ampule (190001C-100mg)
5 mL Clear Glass Sealed Ampule (190001C-500mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Yeast lipids can phase-separate into micrometer-scale membrane domains
Klose C, et al.
The Journal of biological chemistry, 285(39), 30224-30232 (2010)
Global analysis of the yeast lipidome by quantitative shotgun mass spectrometry
Ejsing CS, et al.
Proceedings of the National Academy of Sciences of the USA, 106(7), 2136-2141 (2009)
Changes in lipid metabolism convey acid tolerance in Saccharomyces cerevisiae
Guo ZP, et al.
Biotechnology for Biofuels, 11(1), 1-15 (2018)
Joël S Bloch et al.
Nature, 579(7799), 443-447 (2020-02-28)
In eukaryotic protein N-glycosylation, a series of glycosyltransferases catalyse the biosynthesis of a dolichylpyrophosphate-linked oligosaccharide before its transfer onto acceptor proteins1. The final seven steps occur in the lumen of the endoplasmic reticulum (ER) and require dolichylphosphate-activated mannose and glucose
Budding Yeast: An ideal backdrop for in vivo lipid biochemistry
Singh P
Frontiers in Cell and Developmental Biology, 4, 156-156 (2017)
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