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V3409

Sigma-Aldrich

1-Vinyl-2-pyrrolidinone

contains sodium hydroxide as inhibitor, ≥99%

Synonym(s):

1-Vinyl-2-pyrrolidone

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About This Item

Empirical Formula (Hill Notation):
C6H9NO
CAS Number:
88-12-0
Molecular Weight:
111.14
Beilstein:
110513
EC Number:
201-800-4
MDL number:
MFCD00003197
UNSPSC Code:
12162002
PubChem Substance ID:
24900740
NACRES:
NA.23

vapor density

3.8 (vs air)

Quality Level

200

vapor pressure

0.1 mmHg ( 24 °C)

Assay

≥99%

autoignition temp.

685 °F

contains

sodium hydroxide as inhibitor
100 ppm sodium hydroxide as inhibitor (added to bulk material)

expl. lim.

10 %

refractive index

n20/D 1.512 (lit.)

bp

92-95 °C/11 mmHg (lit.)

density

1.04 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

C=CN1CCCC1=O

InChI

1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2

InChI key

WHNWPMSKXPGLAX-UHFFFAOYSA-N

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General description

1-Vinyl-2-pyrrolidinone is a colorless to yellow liquid, with a characteristic odor. Its melting point is around 13.5oC and boils at about 90-92oC. VP is completely miscible in water and in most organic solvents but partially miscible in aliphatic hydrocarbons. Industrial production of VP by reacting 2-pyrrolidone with acetylene at high pressure and temperature has been reported. The vinylation process proceeds in liquid phase and is catalyzed by 3-pyrrolidone -potassium hydroxide.

Application

1-Vinyl-2-pyrrolidinone (VP) is used in the study of macrophotoinitiator characteristics of poly (vinylchloride) type molecules. Also, used to study the genotoxicity of polyvinylpyrrolidone coated silver nanoparticles.

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - STOT RE 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

203.0 °F - closed cup

Flash Point(C)

95 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Andrew M Telford et al.
Langmuir : the ACS journal of surfaces and colloids, 27(23), 14207-14217 (2011-10-21)
We investigated the dewetting of metastable poly(N-vinylpyrrolidone) (PNVP) thin films (45 nm) on top of polystyrene (PS) thin films (58 nm) as a function of annealing temperature and molecular weight of PS (96 and 6850 kg/mol). We focused on the
Ana C Borges et al.
Acta biomaterialia, 7(9), 3412-3421 (2011-06-10)
The swelling and compressive mechanical behavior as well as the morphology and biocompatibility of composite hydrogels based on Tween® 20 trimethacrylate (T3), N-vinyl-2-pyrrolidone (NVP) and nanofibrillated cellulose (NFC) were assessed in the present study. The chemical structure of T3 was
Kris N J Stevens et al.
Biomaterials, 32(5), 1264-1269 (2010-11-26)
Central venous catheters (CVCs) have become indispensable in the treatment of neonates and patients undergoing chemotherapy or hemodialysis. A CVC provides easy access to the patient's circulation, thus enabling facile monitoring of hemodynamic parameters, nutritional support, or administration of (cytostatic)
Synthesis and characterization of poly (vinylchloride) type macrophotoinitiator comprising side-chain thioxanthone via click chemistry.
Akat H and Ozkan M
Express Polymer Letters, 5(4), 318-326 (2011)
Kamran Qadir et al.
Nano letters, 12(11), 5761-5768 (2012-10-17)
Recent progress in colloidal synthesis of nanoparticles with well-controlled size, shape, and composition, together with development of in situ surface science characterization tools, such as ambient pressure X-ray photoelectron spectroscopy (APXPS), has generated new opportunities to unravel the surface structure
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