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A44509

Sigma-Aldrich

α-Amino-γ-butyrolactone hydrobromide

99%

Synonym(s):

(±)-α-Amino-γ-butyrolactone hydrobromide, DL-Homoserine lactone hydrobromide

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About This Item

Empirical Formula (Hill Notation):
C4H7NO2 · HBr
CAS Number:
6305-38-0
Molecular Weight:
182.02
Beilstein:
4530084
EC Number:
228-614-6
MDL number:
MFCD00012723
UNSPSC Code:
12352202
PubChem Substance ID:
24890868
NACRES:
NA.22

Assay

99%

form

crystalline

color

white to light yellow

mp

220-225 °C (lit.)

application(s)

peptide synthesis

SMILES string

Br[H].NC1CCOC1=O

InChI

1S/C4H7NO2.BrH/c5-3-1-2-7-4(3)6;/h3H,1-2,5H2;1H

InChI key

MKLNTBLOABOJFZ-UHFFFAOYSA-N

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Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Precautionary Statements

P302 + P352 - P305 + P351 + P338

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sigma-Aldrich

B103608

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Steven E A Christiaen et al.
Journal of microbiological methods, 87(2), 213-219 (2011-08-23)
A large number of Gram-negative pathogens produce N-acylhomoserine lactones (AHLs) as signal molecules for quorum sensing (QS). This cell-cell communication system allows them to coordinate gene expression and regulate virulence. Therefore, strategies to inhibit QS are promising for the control
Sandrine Ghirardi et al.
Microbial ecology, 64(3), 725-737 (2012-05-12)
Rhizosphere competence of fluorescent pseudomonads is a prerequisite for the expression of their beneficial effects on plant growth and health. To date, knowledge on bacterial traits involved in rhizosphere competence is fragmented and derived mostly from studies with model strains.
Amanda L May et al.
Analytical chemistry, 84(3), 1243-1252 (2012-01-13)
A range of acylhomoserine lactones (AHLs) are used as intraspecies quorum sensing signals by Gram-negative bacteria, and the detection and quantitation of these molecules is of interest. This manuscript reports a liquid chromatographic-isotope dilution tandem mass spectrometric method for the
Walter Fast et al.
Trends in biochemical sciences, 37(1), 7-14 (2011-11-22)
N-Acyl-L-homoserine lactones (AHLs) are a major class of quorum-sensing signals used by Gram-negative bacteria to regulate gene expression in a population-dependent manner, thereby enabling group behavior. Enzymes capable of generating and catabolizing AHL signals are of significant interest for the
Mijin Kim et al.
Water science and technology : a journal of the International Association on Water Pollution Research, 66(7), 1424-1430 (2012-08-07)
Biofouling control by quorum sensing (QS) inhibition and the influence of membrane surface characteristics on biofilm formation and QS inhibition were investigated. Pseudomonas putida isolated from the bio-fouled reverse osmosis (RO) membranes in a real plant was used. Acylase was
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