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850489

Sigma-Aldrich

L-Tyrosine methyl ester hydrochloride

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About This Item

Linear Formula:
HOC6H4CH2CH(NH2)COOCH3 · HCl
CAS Number:
3417-91-2
Molecular Weight:
231.68
Beilstein:
3917353
EC Number:
222-313-3
MDL number:
MFCD00012607
UNSPSC Code:
12352209
eCl@ss:
32160406
PubChem Substance ID:
24888297
NACRES:
NA.22

form

powder

optical activity

[α]25/D +74.0°, c = 3 in pyridine

reaction suitability

reaction type: solution phase peptide synthesis

mp

192 °C (dec.) (lit.)

application(s)

peptide synthesis

storage temp.

2-8°C

SMILES string

Cl.COC(=O)[C@@H](N)Cc1ccc(O)cc1

InChI

1S/C10H13NO3.ClH/c1-14-10(13)9(11)6-7-2-4-8(12)5-3-7;/h2-5,9,12H,6,11H2,1H3;1H/t9-;/m0./s1

InChI key

VXYFARNRGZWHTJ-FVGYRXGTSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Francesca Fontana et al.
Molecules (Basel, Switzerland), 26(2) (2021-01-14)
Configurationally stable 5-aza[6]helicene (1) was envisaged as a promising scaffold for non-conventional ionic liquids (IL)s. It was prepared, purified, and separated into enantiomers by preparative HPLC on a chiral stationary phase. Enantiomerically pure quaternary salts of 1 with appropriate counterions
A Kawabata et al.
European journal of pharmacology, 233(2-3), 255-260 (1993-03-23)
L-Tyrosine methyl ester (L-Tyr-OMe) produces naloxone-reversible antinociception in mice. This effect was characterized in the present study. L-Tyr-OMe administered s.c. at doses of 100-400 mg/kg elicited dose-dependent antinociception, which was antagonized by s.c. and i.c.v. naloxone at 1 mg/kg and
M Tatsuta et al.
International journal of cancer, 48(5), 785-788 (1991-07-09)
The effect of tyrosine methyl ester (TME) on the incidence, number, and histological types of gastric cancers induced by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) was investigated in male Wistar rats. Rats were subcutaneously given TME, 512 mg/kg body weight, every other day after
T Oishi et al.
Journal of neurochemistry, 42(3), 894-896 (1984-03-01)
Dopamine and norepinephrine concentrations in the stomach, duodenum, and brain were measured after subcutaneous injection of tyrosine methyl ester in the rat. Tyrosine significantly increased dopamine concentrations in each tissue without altering norepinephrine levels. The increase in dopamine concentration in
J Brtko et al.
Molecular and cellular endocrinology, 93(1), 81-86 (1993-05-01)
Various protease inhibitors (e.g. phenylmethanesulfonyl fluoride (PMSF), tosyl-phenylalanine chloromethyl ketone (TosPheCH2Cl)) and substrates (e.g., tosyl-arginine methyl ester (TosArgOMe), tryptophan methyl ester (TrpOMe)) inhibit the binding of adrenal and sex steroids to their cognate receptors (Hubbard and Kalimi (1985) Mol. Cell.
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