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440183

Sigma-Aldrich

(3-Chloropropyl)trimethoxysilane

≥97%

Synonym(s):

δ-Chloropropyltrimethoxysilane, (γ-Chloropropyl)trimethoxysilane, (3-Chloropropyl)trimethoxysilane, 3-(Trimethoxysilyl)propyl chloride

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About This Item

Linear Formula:
Cl(CH2)3Si(OCH3)3
CAS Number:
2530-87-2
Molecular Weight:
198.72
Beilstein:
969627
EC Number:
219-787-9
MDL number:
MFCD00000997
UNSPSC Code:
12352103
PubChem Substance ID:
24867575
NACRES:
NA.23

Assay

≥97%

form

liquid

refractive index

n20/D 1.419 (lit.)

bp

195 °C/750 mmHg (lit.)

density

1.09 g/mL at 25 °C (lit.)

SMILES string

CO[Si](CCCCl)(OC)OC

InChI

1S/C6H15ClO3Si/c1-8-11(9-2,10-3)6-4-5-7/h4-6H2,1-3H3

InChI key

OXYZDRAJMHGSMW-UHFFFAOYSA-N

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General description

(3-Chloropropyl)trimethoxysilane (CPTMS) is an organo-silane which forms a self-assembled monolayer (SAMs) that facilitates the surface modification of different bio-and nano- materials.

Application

(3-Chloropropyl)trimethoxysilane may be used in the synthesis of octakis(3-chloropropyl)octasilsesquioxane.{35}
CPTMS can be used to silanize a variety of nanoparticles like carbon nanotubes (CNT) and silica nanoparticles (SiO2) for different applications like development for molecularly imprinted polymers for protein detection and fabrication of mesoporous silica(organic-inorganic hybrid). It may be used to functionalize silica-iron oxide nanoparticles which can be used as catalysts for the synthesis of pyrano(3,2−c:5,6−c′)dichromene-6,8-dione derivatives.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

161.1 °F - closed cup

Flash Point(C)

71.7 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Marie-Alexandra Neouze et al.
Monatshefte fur chemie, 143(4), 519-525 (2012-01-01)
A newly arising challenge in the field of nanoparticle research concerns the control and the understanding of the interparticle interactions and interparticle properties. This should allow the development of materials based on nanoparticle assemblies which represents a great opportunity to
Feng Wang et al.
Frontiers in bioengineering and biotechnology, 8, 589-589 (2020-07-28)
The juice clarification, one of the key steps in juice processing, suffers from haze formation that results from residual phenolic compounds. In this study, laccase was immobilized on metal-chelated magnetic silica nanoparticles and used for continuous juice clarification in a
M C Neves et al.
Materials today. Bio, 8, 100086-100086 (2020-12-16)
Nucleic acids are relevant biopolymers in therapy and diagnosis, for which their purity and biological activity are of crucial relevance. However, these features are difficult to achieve by cost-effective methods. Herein, we report the functionalization of a macroporous chromatographic support
Durali Mendil et al.
Food chemistry, 221, 1394-1399 (2016-12-17)
A novel and simple solid phase extraction method was improved and recommended for selenium. Silica gel was modified with 2,6-diamino-4-phenil-1,3,5-triazine and characterized by FTIR, SEM and elemental analysis and used adsorbent for column solid phase extraction of selenium ions. The
One-pot synthesis and modification of silica nanoparticles with 3-chloropropyl-trimethoxysilane assisted by microwave irradiation.
De Conto JF, et al.
Chemical Engineering Communications , 205(4), 533-537 (2018)
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