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Key Documents

381306

Sigma-Aldrich

3,3′-Diethylthiatricarbocyanine iodide

99%

Synonym(s):

3-Ethyl-2-[7-(3-ethyl-2-benzothiazolinylidene)-1,3,5-heptatrienyl]benzothiazolium iodide, DTTC iodide, DTTCI, DiSC2(7)

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About This Item

Empirical Formula (Hill Notation):
C25H25IN2S2
CAS Number:
Molecular Weight:
544.51
Beilstein:
3843385
EC Number:
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:
NACRES:
NA.23

Quality Level

Assay

99%

mp

211 °C (dec.) (lit.)

λmax

765 nm

SMILES string

[I-].CCN1\C(Sc2ccccc12)=C\C=C\C=C\C=C\c3sc4ccccc4[n+]3CC

InChI

1S/C25H25N2S2.HI/c1-3-26-20-14-10-12-16-22(20)28-24(26)18-8-6-5-7-9-19-25-27(4-2)21-15-11-13-17-23(21)29-25;/h5-19H,3-4H2,1-2H3;1H/q+1;/p-1

InChI key

OYVFJKVYVDYPFV-UHFFFAOYSA-M

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Application

IR dye

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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B Stieger et al.
Biochimica et biophysica acta, 732(1), 324-326 (1983-07-13)
The sensitivity of the fluorescent dye, 3,3'-diethylthiadicarbocyanine (DiS-C2(5], was too low for the detection of membrane potential changes in rat small intestinal membrane vesicles. Only after adding LaCl3 or after fractionation of the intestinal membranes by free-flow electrophoresis could the
Changning Wang et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 31(7), 2382-2390 (2011-02-18)
Myelination is one of the fundamental biological processes in the development of vertebrate nervous system. Disturbance of myelination is found to be associated with progression in many neurological diseases such as multiple sclerosis. Tremendous efforts have been made to develop
Eddy Kuwana et al.
Biophysical journal, 83(2), 1165-1176 (2002-07-19)
To investigate fluorescence lifetime spectroscopy in tissue-like scattering, measurements of phase modulation as a function of modulation frequency were made using two fluorescent dyes exhibiting single exponential decay kinetics in a 2% intralipid solution. To experimentally simulate fluorescence multiexponential decay
K E Akerman et al.
Journal of neurochemistry, 48(2), 552-559 (1987-02-01)
Membrane potentials of particles present in a subcellular brain preparation, called synaptoneurosomes, have been monitored by measurement of changes in the absorbance of a cyanine dye, DiS-C2-5. The membrane potential of the particles seems to be dependent on both Cl-
Pietro Strobbia et al.
Theranostics, 11(9), 4090-4102 (2021-03-24)
For the majority of cancer patients, surgery is the primary method of treatment. In these cases, accurately removing the entire tumor without harming surrounding tissue is critical; however, due to the lack of intraoperative imaging techniques, surgeons rely on visual

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