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27734

Sigma-Aldrich

Palmitic acid

≥98% palmitic acid basis (GC)

Synonym(s):

1-Pentadecanecarboxylic acid, C16:0, Cetylic acid, Hexadecanoic acid, NSC 5030, PamOH

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About This Item

Linear Formula:
CH3(CH2)14COOH
CAS Number:
Molecular Weight:
256.42
Beilstein:
607489
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21

vapor pressure

10 mmHg ( 210 °C)

Quality Level

Assay

≥98% palmitic acid basis (GC)

form

flakes
powder or crystals

technique(s)

gas chromatography (GC): suitable
thin layer chromatography (TLC): suitable

impurities

≤1% stearic acid (GC)

bp

271.5 °C/100 mmHg (lit.)

mp

61-62.5 °C (lit.)
62-65 °C

acid value

≤240

iodine value

≤0.5

saponification value

≤240

density

0.852 g/mL at 25 °C (lit.)

SMILES string

CCCCCCCCCCCCCCCC(O)=O

InChI

1S/C16H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16(17)18/h2-15H2,1H3,(H,17,18)

InChI key

IPCSVZSSVZVIGE-UHFFFAOYSA-N

Gene Information

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General description

Palmiticacid (C16:0) is a saturated fatty acid commonly found in various naturalsources, such as animal fats and plant oils.

Application

Palmitic acid may be employed in the preparation of palmitic anhydride, via reaction with dicyclohexylcarbodiimide (DCC) in carbon tetrachloride. It undergoes deoxygenation in the presence of 4%wt Pd/C mesoporous catalyst at 300°C and pressure of 17bar of 5% H2 in argon. Aliphatic chain length hydrocarbons containing one less carbon than the corresponding acid were obtained as major products.

Storage Class Code

11 - Combustible Solids

WGK

nwg

Flash Point(F)

235.4 °F

Flash Point(C)

113 °C

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Catalytic deoxygenation of stearic acid and palmitic acid in semibatch mode.
Lestari S, et al.
Catalysis Letters, 130(1-2), 48-51 (2009)
Z Selinger et al.
Journal of lipid research, 7(1), 174-175 (1966-01-01)
A simple method is described for the preparation of caprylic, palmitic, stearic, and oleic anhydrides. Reaction of the free fatty acid and dicyclohexylcarbodiimide in carbon tetrachloride at room temperature gives the corresponding anhydrides in high yield (87-94%).
Xiaozhe Yin et al.
Cell reports, 33(3), 108278-108278 (2020-10-22)
Dendritic cells (DCs) orchestrate the initiation, programming, and regulation of anti-tumor immune responses. Emerging evidence indicates that the tumor microenvironment (TME) induces immune dysfunctional tumor-infiltrating DCs (TIDCs), characterized with both increased intracellular lipid content and mitochondrial respiration. The underlying mechanism
Andrea Felser et al.
Toxicology, 323, 1-9 (2014-06-03)
Dronedarone is an amiodarone-like antiarrhythmic drug associated with severe liver injury. Since dronedarone inhibits mitochondrial respiration and β-oxidation in vitro, mitochondrial toxicity may also explain dronedarone-associated hepatotoxicity in vivo. We therefore studied hepatotoxicity of dronedarone (200mg/kg/day for 2 weeks or
Bruno G Teodoro et al.
Journal of pineal research, 57(2), 155-167 (2014-07-02)
Melatonin has a number of beneficial metabolic actions and reduced levels of melatonin may contribute to type 2 diabetes. The present study investigated the metabolic pathways involved in the effects of melatonin on mitochondrial function and insulin resistance in rat

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