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152307

Sigma-Aldrich

3-Hydroxypyridine-2-carboxylic acid

98%

Synonym(s):

3-Hydroxypicolinic acid, 3-HPA, 3-Hydroxypyridine-2-carboxylic acid

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About This Item

Empirical Formula (Hill Notation):
C6H5NO3
CAS Number:
874-24-8
Molecular Weight:
139.11
Beilstein:
118954
EC Number:
212-859-0
MDL number:
MFCD00006294
UNSPSC Code:
12352100
PubChem Substance ID:
24849221
NACRES:
NA.22

Assay

98%

form

powder or crystals

mp

213-218 °C (lit.)

SMILES string

OC(=O)c1ncccc1O

InChI

1S/C6H5NO3/c8-4-2-1-3-7-5(4)6(9)10/h1-3,8H,(H,9,10)

InChI key

BRARRAHGNDUELT-UHFFFAOYSA-N

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Application

Ligand for a variety of metal complexes including Hg(II), and Sm(III).

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Misaki Nakai et al.
Journal of inorganic biochemistry, 98(1), 105-112 (2003-12-09)
Two chargeless VO(IV) complexes with 3-hydroxypyridine-2-carboxylic acid (H2hpic), [VO(Hhpic-O,O)(Hhpic-O,N)(H2O)].3H2O (1) and the cyclic tetramer [(VO)4(mu-(hpic-O,O',N))4(H2O)4].8H3O (2), have been synthesized and characterized by elemental analysis, mass, infrared, electronic absorption, electron spin resonance (ESR) spectroscopies, and X-ray crystallography. Their coordination structures are
Polyhedron, 26, 1045-1045 (2007)
Polyhedron, 25, 2471-2471 (2006)
E Nordhoff et al.
Nucleic acids research, 22(13), 2460-2465 (1994-07-11)
UV-matrix assisted laser desorption/ionization mass spectrometry (UV-MALDI-MS) with 3-hydroxypicolinic acid as matrix and IR-MALDI-MS with succinic acid as matrix have proved their feasibility for highly accurate and sensitive mass determination of nucleic acids (DNA and RNA). In this work, a
K Tang et al.
Rapid communications in mass spectrometry : RCM, 8(9), 673-677 (1994-09-01)
We found that picolinic acid is a very good matrix for matrix-assisted laser desorption/ionization (MALDI) time-of-flight mass spectrometry of oligonucleotides, proteins and tRNA. Among the oligonucleotides, picolinic acid was shown to be effective for homo-oligonucleotides, d(G)40 and d(C)60, and for
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