Skip to Content
Merck
All Photos(1)

Key Documents

111988

Sigma-Aldrich

Ethyl 4-hydroxybenzoate

ReagentPlus®, 99%

Synonym(s):

Ethylparaben

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
HOC6H4CO2C2H5
CAS Number:
Molecular Weight:
166.17
Beilstein:
1101972
MDL number:
UNSPSC Code:
12352100
eCl@ss:
39024522
PubChem Substance ID:
NACRES:
NA.22

product line

ReagentPlus®

Assay

99%

form

solid

bp

297-298 °C (lit.)

mp

114-117 °C (lit.)

SMILES string

CCOC(=O)c1ccc(O)cc1

InChI

1S/C9H10O3/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H3

InChI key

NUVBSKCKDOMJSU-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

Application

Ethyl 4-hydroxybenzoate (ethylparaben) was used to study the in-situ derivatisation solid-phase microextraction procedure for determining parabens, related chlorophenols, and triclosan in water.
Ethyl 4-hydroxybenzoate, a novel sorbent for solid-phase extraction, was used to study its retention property. It has high extraction efficiency towards the compounds tested owing to the electrostatic interaction, hydrophobic interaction and hydrogen bonding.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Jorge Regueiro et al.
Journal of chromatography. A, 1216(23), 4693-4702 (2009-05-06)
An in situ derivatization solid-phase microextraction method has been developed for the determination of parabens, triclosan and related chlorophenols in water. Acetylated derivatives are selectively determined using gas chromatography with tandem mass spectrometry. Parameters affecting both derivatization and SPME procedures
Shinshi Oishi
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 42(11), 1845-1849 (2004-09-08)
Parabens are alkyl esters of p-hydroxybenzoic acid widely used as preservatives in foodstuffs, cosmetics toiletries and pharmaceuticals. These compounds are known to exert a weak estrogenic activity in estrogen receptor assays in vitro. In addition butyl and propyl parabens show
Tingting Wang et al.
Journal of chromatography. A, 1308, 63-72 (2013-08-21)
A novel sorbent for solid-phase extraction (SPE) was synthesized by chemical immobilization of ampholine on hybrid organic-inorganic silica material. The ampholine-functionalized hybrid organic-inorganic silica sorbent is consisted of aliphatic amine groups, carboxyl groups and long carbon chains, allowing for extraction
Maw-Rong Lee et al.
Journal of chromatography. A, 1120(1-2), 244-251 (2006-03-04)
This study evaluated supercritical fluid extraction (SFE) combined with liquid chromatography-mass spectrometry (LC-MS) to determine trace preservatives and antioxidants including methylparaben (MP), ethylparaben (EP), propylparaben (PP), butylparaben (BP), butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT), alpha-tocopherol (alpha-t) and alpha-tocopherol acetate (alpha-ta)
Christopher Jewell et al.
Toxicology and applied pharmacology, 225(2), 221-228 (2007-09-25)
Parabens are esters of 4-hydroxybenzoic acid and used as anti-microbial agents in a wide variety of toiletries, cosmetics and pharmaceuticals. It is of interest to understand the dermal absorption and hydrolysis of parabens, and to evaluate their disposition after dermal

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service