810332C

18:1 PE CF

Avanti Research^™ - A Croda Brand 810332C

• Synonym(s): 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine-N-(carboxyfluorescein) (ammonium salt)
• Empirical Formula (Hill Notation): C₆₂H₉₄N₃O₁₄P
• CAS Number: 799268-49-8
• Molecular Weight: 1136.40
• UNSPSC Code: 12352211
• NACRES: NA.25

Properties

• Assay: >99% (TLC)
• form: solution
• packaging: pkg of 1 × 1 mL (810332C-1mg); pkg of 5 × 1 mL (810332C-5mg); pkg of 5 × 2 mL (810332C-10mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 810332C
• concentration: 1 mg/mL (810332C-10mg); 1 mg/mL (810332C-1mg); 1 mg/mL (810332C-5mg)
• shipped in: dry ice
• storage temp.: −20°C

Description

General description

Phosphoethanolamine (PHOS) is a precursor to phosphatidylcholine and phosphatidylethanolamine. 18:1 PE CF is a green fluorescent tagged phosphatidylethanolamine.

Application

18:1 PE CF may be used:

• to spike human serum
• to prepare concentrated lipid mix, PC:PE:fluoPE to assess basal binding properties and PC:PE:fluoPE:PIP to assess specific binding properties of the protein to each phosphoinositides (PIP)
• to prepare the large unilamellar vesicles (LUVs)
• in the preparation of fluorescent phosphoinositide?containing liposomes
• for fluorescent labeling of total lipids to the initial liposome formulation mixture
• in the formulation of pegylated magneto-liposomes (MLs) and transferrin (Tf) embedding

Biochem/physiol Actions

Phosphatidylethanolamine controls the membrane fluidity in eukaryotic cells. Phosphoethanolamine (PHOS) has the ability to repress tumour growth both in vitro and in vivo. It possesses anticarcinogenic effects. It can also prevent the mRNA expression of cyclin D1 and VEGFR1 (vascular endothelial growth factor receptor 1).

Packaging

5 mL Amber Glass Screw Cap Vial (810332C-10mg)

5 mL Amber Glass Screw Cap Vial (810332C-1mg)

5 mL Amber Glass Screw Cap Vial (810332C-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H302,H315,H319,H331,H336,H351,H361d,H372
• Precautionary Statements: P202 - P301 + P312 - P302 + P352 - P304 + P340 + P311 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 Oral - STOT SE 3
• Target Organs: Central nervous system, Liver,Kidney
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3