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Sigma-Aldrich

2-Hydroxy-2-methylpropiophenone

97%

Synonym(s):

1-Hydroxy-1-methylethyl phenyl ketone, 1-Phenyl-2-methyl-2-hydroxypropanone, 2-Hydroxy-2-methyl-1-phenyl-1-propanone, 2-Methyl-3-phenyl-3-oxopropan-2-ol

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About This Item

Linear Formula:
C6H5COC(CH3)2OH
CAS Number:
Molecular Weight:
164.20
EC Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

Assay

97%

form

liquid

refractive index

n20/D 1.533 (lit.)

bp

102-103 °C/4 mmHg (lit.)

density

1.077 g/mL at 25 °C (lit.)

SMILES string

CC(C)(O)C(=O)c1ccccc1

InChI

1S/C10H12O2/c1-10(2,12)9(11)8-6-4-3-5-7-8/h3-7,12H,1-2H3

InChI key

XMLYCEVDHLAQEL-UHFFFAOYSA-N

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General description

2-Hydroxy-2-methylpropiophenone is a radical photoinitiator (PI) molecule that can be used in the crosslinking of polymers by the exposure of UV radiation. It can be used in the development of UV curable resins for exterior coating applications.

Application

  • Photochemical Thiol-Ene “Click” Chemistry: The study utilized 2-hydroxy-2-methylpropiophenone for the synthesis of highly functional polyols by photochemical thiol-ene “click” chemistry (M Ionescu, A Garcia-Comer, T Spidel, 2023).
  • Development of Water-Soluble Type I Photoinitiators: This study focused on the development of new water-soluble type I photoinitiators for hydrogel synthesis using 2-hydroxy-2-methylpropiophenone, enhancing the understanding of photopolymerization processes (B Aubry, F Dumur, M Lansalot, E Bourgeat-Lami, 2022).

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Chronic 3

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

251.6 °F - closed cup

Flash Point(C)

122 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Anirudha Banerjee et al.
Science advances, 5(8), eaax1893-eaax1893 (2019-08-28)
Structures and particles that slowly release solute into solution can attract or repel other particles in suspension via diffusiophoresis, a process we termed "soluto-inertial (SI) interactions." These SI interactions involve "beacons" that establish and sustain nonequilibrium solute fluxes over long
Lu Li et al.
Polymers, 12(1) (2020-01-18)
The detection of p-nitrophenol (PNP) is of great significance for assessment of environment pollution and potential health risks. In this study, based on inverse opal polymeric photonic crystals (IOPPCs), a selective and visual sensor for high-performance PNP detection is developed.
Xuehua Zhang et al.
Proceedings of the National Academy of Sciences of the United States of America, 112(30), 9253-9257 (2015-07-15)
Nanodroplets on a solid surface (i.e., surface nanodroplets) have practical implications for high-throughput chemical and biological analysis, lubrications, laboratory-on-chip devices, and near-field imaging techniques. Oil nanodroplets can be produced on a solid-liquid interface in a simple step of solvent exchange
Elaboration of a fire retardant coating for polyamide-6 using cold plasma polymerization of a fluorinated acrylate
Errifai I, et al.
Surface and Coatings Technology, 180(13), 297-301 (2004)
Photopatternable conductive PDMS materials for microfabrication
Cong H and Pan T
Advances in Functional Materials, 18(13), 1912-1921 (2008)

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