- B-(3,3-difluoroallyl)diisopinocampheylborane for the enantioselective fluoroallylboration of aldehydes.
B-(3,3-difluoroallyl)diisopinocampheylborane for the enantioselective fluoroallylboration of aldehydes.
The Journal of organic chemistry (2012-09-15)
P Veeraraghavan Ramachandran, Agnieszka Tafelska-Kaczmarek, Anamitra Chatterjee
PMID22973971
要旨
The fluoroallylboration of aldehydes with B-(3,3-difluoroallyl)diisopinocampheylborane, which was prepared via the hydroboration of 1,1-difluoroallene, provides chiral 2,2-gem-difluorinated homoallylic alcohols in good yields and 91-97% ee.