- Discovery of a β-glucosidase inhibitor from a chemically engineered extract prepared through sulfonylation.
Discovery of a β-glucosidase inhibitor from a chemically engineered extract prepared through sulfonylation.
Molecular diversity (2011-01-06)
Mario O Salazar, Oscar Micheloni, Andrea M Escalante, Ricardo L E Furlan
PMID21207143
要旨
A semisynthetic β-glucosidase inhibitor was identified from a chemically engineered extract prepared by reaction with benzenesulfonyl chloride. The structure includes a natural histamine portion and a benzenesulfonyl portion introduced during the diversification step.