A labdane diterpene glucoside from the rhizomes of Curcuma mangga.

A labdane diterpene glucoside from the rhizomes of Curcuma mangga.

Journal of natural products (2005-07-26)

Faridah Abas, Nordin H Lajis, Khozirah Shaari, Daud Ahmad Israf, Johnson Stanslas, Umi Kalsom Yusuf, Salahuddin Mohd Raof

PMID16038556

要旨

A new labdane diterpene glucoside, curcumanggoside (1), together with nine known compounds, including labda-8(17),12-diene-15,16-dial (2), calcaratarin A (3), zerumin B (4), scopoletin, demethoxycurcumin, bisdemethoxycurcumin, 1,7-bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one, curcumin, and p-hydroxycinnamic acid, have been isolated from the rhizomes of Curcuma mangga. Their structures were determined using a combination of 1D (1H NMR, 13C NMR, DEPT) and 2D (COSY, HSQC, HMBC) NMR techniques. All diarylheptanoids and scopoletin showed significant antioxidant activity. Zerumin B, demethoxycurcumin, bisdemethoxycurcumin, and curcumin also exhibited cytotoxic activity against a panel of five human tumor cell lines.

材料

製品番号

ブランド

製品内容

B1378

Sigma-Aldrich

2,6-ジ-tert-ブチル-4-メチルフェノール, ≥99.0% (GC), powder

W218405

Sigma-Aldrich

ブチル化ヒドロキシトルエン, ≥99%, FCC, FG

47168

Supelco

3,5-ジ-tert-ブチル-4-ヒドロキシトルエン, analytical standard

T3634

Sigma-Aldrich

(+)-α-トコフェロール, from vegetable oil, Type V, ~1000 IU/g

S2500

Sigma-Aldrich

スコポレチン, ≥99%

T1539

Sigma-Aldrich

(+)-α-トコフェロール, Type VI, from vegetable oil, liquid (≥0.88M based on potency, density and molecular wt.), BioReagent, suitable for insect cell culture, ≥1000 IU/g

34750

Sigma-Aldrich

2,6-ジ-tert-ブチル-4-メチルフェノール, purum, ≥99.0% (GC)

03762

Sigma-Aldrich

2,6-ジ-tert-ブチル-4-メチルフェノール, tested according to Ph. Eur.

90594

Supelco

ビスデメトキシクルクミン, analytical standard