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Merck
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資料

51656-U

Supelco

Ascentis® Express 90Å C8 (2 μm) HPLC Columns

L × I.D. 5 cm × 2.1 mm UHPLC Column

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About This Item

UNSPSCコード:
41115700
NACRES:
SB.52

product name

Ascentis® Express C8, 2 μm UHPLC Column, 2 μm particle size, L × I.D. 5 cm × 2.1 mm

物質

stainless steel column

品質水準

100

認証

suitable for USP L7

製品種目

Ascentis®

特徴

endcapped

メーカー／製品名

Ascentis®

包装

1 ea of

パラメーター

1000 bar max. pressure (14500 psi)
60 °C temp. range

テクニック

LC/MS: suitable
UHPLC-MS: suitable
UHPLC: suitable

L × 内径

5 cm × 2.1 mm

表面積

120 m2/g

不純物

<5 ppm (metals)

マトリックス

Fused-Core particle platform
superficially porous particle

マトリックス活性基

dimethyloctyl phase

粒径

2 μm

ポアサイズ

90 Å pore size

pH

2-9

アプリケーション

food and beverages

分離法

reversed phase

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詳細

Ascentis® Express 2μm C8 UHPLC columns are based on a 90 Å Fused-Core® particle design. The Fused-Core particle provides a thin porous shell of high-purity silica surrounding a solid silica core. This particle design exhibits very high column efficiency due to the shallow diffusion paths in the 0.4-micron thick porous shell and the small overall particle size of 2-microns. The densely bonded, extensively endcapped dimethyloctyl stationary phase of Ascentis Express 2μm C8 provides a stable, reversed-phase packing that can be used for basic, acidic, or neutral compounds.

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法的情報

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany
Fused-Core is a registered trademark of Advanced Materials Technology, Inc.

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試験成績書（COA）

Lot/Batch Number
USLKM001316
USLKM001315
USLKM001314
USLKM001313
USLKM001306

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Sreenivasa Rao Chitturi et al.
Journal of pharmaceutical and biomedical analysis, 55(1), 31-47 (2011-02-15)
This paper proposes a simple and selective RP-HPLC method for the determination of process impurities and degradation products (degradants) of atazanavir sulfate (ATV) drug substance. Chromatographic separation was achieved on Ascentis(®) Express C8, (150mm×4.6mm, 2.7μm) column thermostated at 30°C under
Ugandar Reddy Inugala et al.
Journal of chromatographic science, 51(5), 453-459 (2012-10-13)
This paper describes the development of a rapid, novel, stability-indicating gradient reversed-phase high-performance liquid chromatographic method and associated system suitability parameters for the analysis of naproxcinod in the presence of its related substances and degradents using a quality-by-design approach. All
Luigi Silvestro et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878(30), 3134-3142 (2010-10-20)
Quantitative methods using LC-MS/MS allow achievement of adequate sensitivity for pharmacokinetic studies with clopidogrel; three such methods, with LLOQs as low as 5 pg/mL, were developed and fully validated according to the well established FDA 2001 guidelines. The chromatographic separations
Han Young Eom et al.
Journal of chromatography. A, 1217(26), 4347-4354 (2010-05-11)
Saikosaponins are triterpene saponins derived from the roots of Bupleurum falcatum L. (Umbelliferae), which has been traditionally used to treat fever, inflammation, liver diseases, and nephritis. It is difficult to analyze saikosaponins using HPLC-UV due to the lack of chromophores.
Federica Pellati et al.
Journal of pharmaceutical and biomedical analysis, 81-82, 126-132 (2013-05-07)
A closed-vessel microwave-assisted extraction (MAE) technique was optimized for the first time for the extraction of polyphenols from raw propolis. The results obtained by means of response surface experimental design methodology showed that the best global response was reached when
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資料

Ascentis® Express C8 U/HPLC Columns

When a C18 doesn′t give the desired separation, or your sample contains compounds that are known to be difficult to retain or resolve on a C18, consider changing to an Ascentis® Express C8 column.

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