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Merck

WH0009189M1

Sigma-Aldrich

Monoclonal Anti-ZBED1 antibody produced in mouse

clone 5G1, purified immunoglobulin, buffered aqueous solution

別名:

Anti-ALTE, Anti-KIAA0785, Anti-TRAMP, Anti-zinc finger, BED-type containing 1

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About This Item

UNSPSCコード:
12352203
NACRES:
NA.41

由来生物

mouse

品質水準

結合体

unconjugated

抗体製品の状態

purified immunoglobulin

抗体製品タイプ

primary antibodies

クローン

5G1, monoclonal

形状

buffered aqueous solution

化学種の反応性

human

テクニック

indirect ELISA: suitable
indirect immunofluorescence: suitable
western blot: 1-5 μg/mL

アイソタイプ

IgG2aκ

GenBankアクセッション番号

UniProtアクセッション番号

輸送温度

dry ice

保管温度

−20°C

ターゲットの翻訳後修飾

unmodified

遺伝子情報

human ... ZBED1(9189)

詳細

Zinc finger, BED-type containing 1 (ZBED1), also known as DNA replication-related element-binding factor (DREF), is encoded by the single-exon gene mapped to Xp/Yp PAR region that has a functional homolog on the Y chromosome and escapes X-inactivation.

免疫原

ZBED1 (NP_004720, 3 a.a. ~ 99 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
NKSLESSQTDLKLVAHPRAKSKVWKYFGFDTNAEGCILQWKKIYCRICMAQIAYSGNTSNLSYHLEKNHPEEFCEFVKSNTEQMREAFATAFSKLKP

生物化学的/生理学的作用

Zinc finger, BED-type containing 1 (ZBED1) function as a crucial transcription factor for cell proliferation, and is implicated in cell cycle-dependent regulation of a number of ribosomal protein (RP) genes. The encoded protein has been suggested to be involved in the transposition of other transposable elements.

物理的形状

Solution in phosphate buffered saline, pH 7.4

法的情報

GenBank is a registered trademark of United States Department of Health and Human Services

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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保管分類コード

10 - Combustible liquids

引火点(°F)

Not applicable

引火点(℃)

Not applicable

個人用保護具 (PPE)

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


適用法令

試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。

Jan Code

WH0009189M1-100UG:


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Sofie Traynor et al.
Nucleic acids research, 47(13), 6668-6684 (2019-05-23)
Rearrangement of the 1q12 pericentromeric heterochromatin and subsequent amplification of the 1q arm is commonly associated with cancer development and progression and may result from epigenetic deregulation. In many premalignant and malignant cells, loss of 1q12 satellite DNA methylation causes
T Esposito et al.
Human molecular genetics, 8(1), 61-67 (1999-01-15)
We report the cloning of a novel gene, called Tramp, in the Xp/Yp PAR region that has a functional homologue on the Y chromosome and escapes X-inactivation. This gene encodes, within a single exon, a putative protein that has amino
Simone Johansen et al.
Genes, 13(1) (2022-01-22)
The transcription factor ZBED1 is highly expressed in trophoblast cells, but its functions in the processes of trophoblast and placental biology remain elusive. Here, we characterized the role of ZBED1 in trophoblast cell differentiation using an in vitro BeWo cell
A Helena Mangs et al.
Current genomics, 8(2), 129-136 (2008-07-29)
The pseudoautosomal regions (PAR1 and PAR2) of the human X and Y chromosomes pair and recombine during meiosis. Thus genes in this region are not inherited in a strictly sex-linked fashion. PAR1 is located at the terminal region of the
Daisuke Yamashita et al.
Molecular and cellular biology, 27(6), 2003-2013 (2007-01-16)
Although ribosomal proteins (RPs) are essential cellular constituents in all living organisms, mechanisms underlying regulation of their gene expression in mammals remain unclear. We have established that 22 out of 79 human RP genes contain sequences similar to the human

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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