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About This Item
実験式（ヒル表記法）:
C6H13N3O2S
CAS番号:
分子量:
191.25
Beilstein:
6844478
MDL番号:
UNSPSCコード:
12352204
由来生物
synthetic
フォーム
solid
色
white
溶解性
H2O: >10 mg/mL
保管温度
2-8°C
SMILES記法
N[C@@H](CCCNC(N)=S)C(O)=O
InChI
1S/C6H13N3O2S/c7-4(5(10)11)2-1-3-9-6(8)12/h4H,1-3,7H2,(H,10,11)(H3,8,9,12)/t4-/m0/s1
InChI Key
BKGWACHYAMTLAF-BYPYZUCNSA-N
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生物化学的／生理学的作用
Potent and selective inhibitor of neuronal and endothelial isoforms of nitric oxide synthase.
保管分類コード
11 - Combustible Solids
WGK
WGK 3
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
Eyeshields, Gloves, type N95 (US)
最新バージョンのいずれかを選択してください：
H M Abu-Soud et al.
The Journal of biological chemistry, 269(51), 32318-32326 (1994-12-23)
Heme iron reduction in the nitric-oxide synthases (NOSs) requires calmodulin binding and is associated with increased NO synthesis and NADPH oxidation (Abu-Soud, H. M., and Stuehr, D. J. (1993) Proc. Natl. Acad. Sci., U. S. A. 90, 10769-10772). Here, we
E S Furfine et al.
The Journal of biological chemistry, 269(43), 26677-26683 (1994-10-28)
Potent and selective inhibition of neuronal nitric oxide synthase (nNOS) compared to endothelial NOS (eNOS) and inducible NOS (iNOS) may be useful to treat cerebral ischemia (stroke) and other neurodegenerative diseases. S-Methyl-L-thiocitrulline (Me-TC) and S-ethyl-L-thiocitrulline (Et-TC) inhibited the oxidation of
C Frey et al.
The Journal of biological chemistry, 269(42), 26083-26091 (1994-10-21)
Nitric-oxide synthase (NOS) catalyzes the oxidation of L-arginine to citrulline and nitric oxide (NO). The enzyme is inhibited by a variety of N omega-monosubstituted L-arginine analogs, and some of these compounds are useful in reversing pathologies associated with the overproduction
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