SRP3304

INSL5/INSL7 HYBRID human

recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC)

• 別名: none
• UNSPSCコード: 12352200
• NACRES: NA.32

特性

• 由来生物: human
• リコンビナント: expressed in E. coli
• アッセイ: ≥98% (HPLC); ≥98% (SDS-PAGE)
• 形状: lyophilized
• 分子量: 5.7 kDa
• 包装: pkg of 25 μg
• 不純物: <0.1 EU/μg endotoxin, tested
• 色: white to off-white
• UniProtアクセッション番号: Q9Y5Q6 / Q8WXF3
• 輸送温度: wet ice
• 保管温度: −20°C
• 遺伝子情報: human ... INSL5(10022) , RLN3(117579)

詳細

生物化学的／生理学的作用

The Insulin/Relaxin structural family of proteins consists of at least seven members, each containing an Insulin-like hetero-dimeric structure consisting of two polypeptide chains held together by two inter-chain disulfide bonds. INSL7-INSL5 hybrid contains the B-chain of INSL7 (Relaxin-3), linked to the A-chain of INSL5. The INSL7-INSL5 hybrid protein can specifically activate the G protein coupled receptors, GPCR135 and GPCR142, but unlike Relaxin-3, does not induce significant activation of the LGR7 receptor. Recombinant INSL7-INSL5 hybrid is a hetero-dimeric 5.7 kDa protein consisting of a 27 amino acid B-chain disulfide linked to a 21 amino acid A-chain.

物理的形状

Lyophilized with no additives.

再構成

Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable