SAB5702616

Anti-OPRD1 Antibody, clone 1R4W8, Rabbit Monoclonal

• 別名: OPRD
• UNSPSCコード: 12352203
• NACRES: NA.46

特性

• 由来生物: rabbit
• 品質水準: 100
• 物質: colorless
• クローン: 1R4W8, monoclonal
• 形状: liquid
• 分子量: 45 kDa
• 化学種の反応性: rat, human, rat
• 濃度: 1.1 mg/mL
• テクニック: western blot: 1:500 - 1:2000
• 色: colorless
• アイソタイプ: IgG
• 免疫原配列: MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATS
• UniProtアクセッション番号: P41143
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... OPRD1(4985)

詳細

詳細

G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human OPRD1 (P41143).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

アプリケーション

WB

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1