SAB4503999

Anti-phospho-TIE2 (pTyr¹¹⁰⁸) antibody produced in rabbit

affinity isolated antibody

• 別名: Anti-CD202B, Anti-GLC3E, Anti-TIE-2, Anti-VMCM, Anti-VMCM1
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: antigen 125 kDa
• 化学種の反応性: mouse, rat, human
• 濃度: ~1 mg/mL
• テクニック: ELISA: 1:10000; immunofluorescence: 1:100-1:500; western blot: 1:500-1:1000
• NCBIアクセッション番号: Q02763
• UniProtアクセッション番号: Q02763
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: phosphorylation (pTyr1108)
• 遺伝子情報: human ... TEK(7010)

詳細

詳細

The TIE2 (TEK receptor tyrosine kinase) is also termed as TEK (tyrosine-protein kinase receptor). This gene is located on human chromosome 9p21.2. It is expressed in the Schlemm′s canal endothelial of the eye. TIE2 belongs to the receptor tyrosine kinases family.

免疫原

The antiserum was produced against synthesized peptide derived from human TIE2 around the phosphorylation site of Tyr1108.

Immunogen Range: 1074-1123

生物化学的／生理学的作用

Tie-2 (TEK receptor tyrosine kinase) protein induces angiogenesis and supports endothelial cell survival, upon binding of angiopoietin-1 (an endothelial growth factor) to the receptor. This gene is necessary for Schlemm′s canal formation. This gene regulates vascular homeostasis by involving in auto or transphosphorylation. Tie-2 is essential for the growth of vascular structures during embryogenesis.

特徴および利点

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物理的形状

ウサギIgGのPBS溶液（Mg2+およびCa2+を含まず）、pH 7.4、150 mM NaCl、0.02％ アジ化ナトリウム、50％ グリセロール

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable