由来生物
rabbit
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
フォーム
buffered aqueous solution
分子量
antigen 36 kDa
交差性
mouse, human
濃度
~1 mg/mL
テクニック
ELISA: 1:40000
western blot: 1:500-1:1000
NCBIアクセッション番号
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... ELOV4(6785)
詳細
Anti-ELOVL4 antibody detects endogenous levels of total ELOVL4 protein.
The ELOVL4 (elongation of very long chain fatty acids protein 4) gene is mapped to human chromosome 6q14.1. The encoded protein localizes to endoplasmic reticulum. ELOVL4 protein consists of five transmembrane domains, a histidine cluster motif and di-lysine motif at the C-terminus.
免疫原
The antiserum was produced against synthesized peptide derived from human ELOVL4.
Immunogen Range: 41-90
Immunogen Range: 41-90
生物化学的/生理学的作用
ELOVL4 (elongation of very long chain fatty acids protein 4) plays an important role in the biosynthesis of very long chain fatty acids (both saturated and unsaturated) in the retina, meibomian gland, skin, testis and brain. Mutation in the gene causes autosomal dominant Stargardt3 macular dystrophy. Variation in ELOVL4 results in spastic quadriplegia, ichthyosis and intellectual disability leading to neuro-ichthyotic disorder.
特徴および利点
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
物理的形状
ウサギIgGのPBS溶液(Mg2+およびCa2+を含まず)、pH 7.4、150 mM NaCl、0.02% アジ化ナトリウム、50% グリセロール
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
12 - Non Combustible Liquids
WGK
nwg
引火点(°F)
Not applicable
引火点(℃)
Not applicable
最新バージョンのいずれかを選択してください:
Different Mutations in ELOVL4 Affect Very Long Chain Fatty Acid Biosynthesis to Cause Variable Neurological Disorders in Humans.
Agbaga MP
Advances in Experimental Medicine and Biology, 854, 129-135 (2016)
Dominant Stargardt Macular Dystrophy (STGD3) and ELOVL4.
Logan S and Anderson RE
Advances in Experimental Medicine and Biology, 801, 447-453 (2014)
A novel recessive mutation in the gene ELOVL4 causes a neuro-ichthyotic disorder with variable expressivity.
Mir H
BMC Medical Genetics, 15:25, 1-5 (2014)
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