SAB4502055

Anti-OVOL1 antibody produced in rabbit

affinity isolated antibody

• 別名: OVOL1, Putative transcription factor Ovo-like 1, hOvo1
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: antigen 30 kDa
• 化学種の反応性: human, mouse
• 濃度: ~1 mg/mL
• テクニック: ELISA: 1:40000; western blot: 1:500-1:1000
• NCBIアクセッション番号: O14753
• UniProtアクセッション番号: O14753
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... OVOL1(5017)

詳細

詳細

Anti-OVOL1 antibody detects endogenous levels of total OVOL1 protein.

The OVOL1 (ovo like transcriptional repressor 1) gene is mapped to human chromosome 11q13.1. It is widely conserved. In mammals, the gene encodes for C₂H₂ zinc finger transcription factor. It is predominantly expressed in the human placenta and in the inner root sheath of the hair follicle, suprabasal layer of the epidermis, the ductal portion of the eccrine glands and mature sebocytes of the skin.{36] The protein is localized to cytoplasm.

免疫原

The antiserum was produced against synthesized peptide derived from human OVOL1.

Immunogen Range: 1-50

生物化学的／生理学的作用

The protein encoded by the OVOL1 (ovo like transcriptional repressor 1) gene regulates proliferation and differentiation of epithelial cells. This protein is homologous to that in Drosophila species, which regulates trophoblast differentiation. OVOL1 is known to take part in epidermal keratinisation by inducing differentiation. OVOL1 is associated with atopic dermatitis. OVOL1 is associated with skin morphogenesis and tumorigenesis.

特徴および利点

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物理的形状

ウサギIgGのPBS溶液（Mg2+およびCa2+を含まず）、pH 7.4、150 mM NaCl、0.02％ アジ化ナトリウム、50％ グリセロール

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable