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由来生物
rabbit
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
形状
buffered aqueous solution
分子量
antigen 40 kDa
化学種の反応性
human
濃度
~1 mg/mL
テクニック
ELISA: 1:5000
western blot: 1:500-1:1000
NCBIアクセッション番号
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... OPRD(4985)
詳細
Anti-OPRD1 antibody detects endogenous levels of total OPRD1 protein.
The OPRD1 (opioid receptor δ1) gene is mapped to human chromosome 1p35.3 and encodes for a G-protein-coupled receptor. It is abundantly expressed in peripheral tissues.
免疫原
The antiserum was produced against synthesized peptide derived from human OPRD1.
Immunogen Range: 311-360
Immunogen Range: 311-360
生物化学的／生理学的作用
OPRD1 (opioid receptor δ1) is associated with cognitive function and mood driven behavior. Anxiolytic and antidepressant actions are brought about when specific agonists bind to the OPRD1 gene. δ-opioid receptor (DOR) is known to be involved in the progression and development of specific tumours (malignant). Upregulation of this gene is observed in breast cancer, and thus, it can serve as an important therapeutic marker.
特徴および利点
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
物理的形状
ウサギIgGのPBS溶液（Mg2+およびCa2+を含まず）、pH 7.4、150 mM NaCl、0.02％ アジ化ナトリウム、50％ グリセロール
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保管分類コード
10 - Combustible liquids
WGK
nwg
引火点(°F)
Not applicable
引火点(℃)
Not applicable
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Louis Gendron et al.
Pharmacological reviews, 68(3), 631-700 (2016-06-28)
Opioids are among the most effective analgesics available and are the first choice in the treatment of acute severe pain. However, partial efficacy, a tendency to produce tolerance, and a host of ill-tolerated side effects make clinically available opioids less
Yang-Chao Wei et al.
Oncology reports, 36(5), 2579-2586 (2016-10-26)
δ‑opioid receptor (DOR) belongs to the family of G protein‑coupled receptors (GPCRs). Numerous studies have shown that DOR is widely distributed in human peripheral tissues and is closely related to the development and progression of certain malignant tumours. However, there is controversy in
Ann M Manzardo et al.
Gene, 560(2), 184-194 (2015-02-07)
Alcoholism arises from combined effects of multiple biological factors including genetic and non-genetic causes with gene/environmental interaction. Intensive research and advanced genetic technology has generated a long list of genes and biomarkers involved in alcoholism neuropathology. These markers reflect complex
Huihui Ji et al.
PloS one, 12(3), e0172335-e0172335 (2017-03-03)
Aberrant DNA methylation has been observed in the patients with Alzheimer's disease (AD), a common neurodegenerative disorder in the elderly. OPRD1 encodes the delta opioid receptor, a member of the opioid family of G-protein-coupled receptors. In the current study, we
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