由来生物
rabbit
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
形状
buffered aqueous solution
分子量
antigen 109 kDa
化学種の反応性
human, mouse
濃度
~1 mg/mL
テクニック
ELISA: 1:5000
western blot: 1:500-1:1000
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
保管温度
−20°C
遺伝子情報
human ... KIT(3815)
詳細
Anti-KIT Antibody detects endogenous levels of total KIT protein.
KIT (proto-oncogene) is a type III receptor tyrosine kinase (RTK). It codes for a tyrosine kinase receptor (CD117). It is located on human chromosome 4q12.
免疫原
The antiserum was produced against synthesized peptide derived from human KIT.
Immunogen Range: 906-955
Immunogen Range: 906-955
生物化学的／生理学的作用
KIT (proto-oncogene) participates in cell signal transduction. It also participates in the progression of hematopoietic stem cells, melanocytes, germ cells, mast cells and interstitial cells of Cajal. Mutations in KIT gene results in gastrointestinal stromal tumors.
特徴および利点
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
物理的形状
ウサギIgGのPBS溶液（Mg2+およびCa2+を含まず）、pH 7.4、150 mM NaCl、0.02％ アジ化ナトリウム、50％ グリセロール
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
12 - Non Combustible Liquids
WGK
nwg
引火点(°F)
Not applicable
引火点(℃)
Not applicable
試験成績書（COA）
製品のロット番号・バッチ番号を入力して、試験成績書（COA） を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
Yu Wang et al.
Cell communication and signaling : CCS, 16(1), 16-16 (2018-04-18)
Gain-of-function mutations and overexpression of KIT are characteristic features of gastrointestinal stromal tumor (GIST). Dysregulation in miRNA expression may lead to KIT overexpression and tumorigenesis. miRNA microarray analysis and real-time PCR were used to determine the miRNA expression profiles in
Loss of c-KIT expression in thyroid cancer cells.
Franceschi S, et al.
PLoS ONE, 12(3) (2017)
KIT extracellular and kinase domain mutations in gastrointestinal stromal tumors
Lux ML, et al.
The American Journal of Pathology, 156(3), 791-795 (2000)
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