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由来生物
rabbit
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
形状
buffered aqueous solution
分子量
antigen 46 kDa
化学種の反応性
human, rat, mouse
濃度
~1 mg/mL
テクニック
ELISA: 1:20000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... ADRB2(154)
詳細
Anti-ADRB2 Antibody detects endogenous levels of total ADRB2 protein.
Adrenoceptor β 2/β2 adrenergic receptor (ADRB2), a transmembrane protein, belongs to the superfamily of G-protein coupled receptors (GPCRs). This protein is expressed in skeletal muscle, mast cells, lymphocytes, airway smooth muscle, epithelial and endothelial cells of the lung, the smooth muscle of blood vessels, oral and skin keratinocytes. It comprises seven transmembrane domains and three extracellular and three intracellular loops. ADRB2 gene is located on human chromosome 5q32. Anti-ADRB2 Antibody detects endogenous levels of total ADRB2 protein.
免疫原
The antiserum was produced against synthesized peptide derived from human ADRB2.
Immunogen Range: 201-250
Immunogen Range: 201-250
生物化学的/生理学的作用
Adrenoceptor β 2/β2 adrenergic receptor (ADRB2) binding to agonist activates Gs protein. Variation in the ADRB2 gene is involved in blood pressure (BP) and body mass index (BMI). ADRB2 is associated with nasopharyngeal carcinoma.
特徴および利点
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
物理的形状
ウサギIgGのPBS溶液(Mg2+およびCa2+を含まず)、pH 7.4、150 mM NaCl、0.02% アジ化ナトリウム、50% グリセロール
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
nwg
引火点(°F)
Not applicable
引火点(℃)
Not applicable
試験成績書(COA)
製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。
The American journal of physiology, 276(4), H1379-H1384 (1999-04-13)
Glucocorticoids and catecholamines exert important effects on cardiovascular physiology and metabolism. Variants of the glucocorticoid receptor gene (GRL) and the beta2-adrenergic receptor gene (ADRB2) have been associated with high blood pressure and obesity. These genes are close on human chromosome
ADRB2 (adrenoceptor beta 2, surface)
Atlas of Genetics and Cytogenetics in Oncology and Haematology (2021)
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