SAB4300045

Anti-phospho-NBN (pSer³⁴³) antibody produced in rabbit

affinity isolated antibody

• 別名: Anti-AT-V1 antibody produced in rabbit, Anti-AT-V2 antibody produced in rabbit, Anti-ATV antibody produced in rabbit, Anti-FLJ10155 antibody produced in rabbit, Anti-nibrin antibody produced in rabbit
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: ~95 kDa
• 化学種の反応性: human
• 濃度: 1 mg/mL
• テクニック: western blot: 1:500-1:1000
• アイソタイプ: IgG
• 免疫原配列: (S-L-SP-Q-G)
• NCBIアクセッション番号: NP_002476.2
• UniProtアクセッション番号: O60934
• 輸送温度: wet ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: phosphorylation (pSer343)
• 遺伝子情報: human ... NBN(4683)

詳細

免疫原

Peptide sequence around phosphorylation site of serine 343 (S-L-S(p)-Q-G), according to the protein NBN.

特徴および利点

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ターゲットの説明

Mutations in p95/NBS1 gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.

物理的形状

PBS（0.02％ アジ化ナトリウム、50％ グリセロール含有）

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable