SAB4200551

抗MST1R抗体 ウサギ宿主抗体

~1.0 mg/mL, affinity isolated antibody

• 別名: 抗CDw136抗体, 抗p185-Ron抗体
• UNSPSCコード: 12352203
• NACRES: NA.44

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: antigen ~170 kDa
• 化学種の反応性: rat, human
• 濃度: ~1.0 mg/mL
• テクニック: western blot: 2.5-5.0 μg/mL using whole extracts of human HT-29 cells.
• UniProtアクセッション番号: Q04912
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... MST1R(4486) ; rat ... Mst1r(300999)

詳細

詳細

Macrophage-stimulating protein receptor (MST1R) is a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. It is a heterodimer of disulfide-linked α- and β-subunits, generated by proteolytic cleavage of a single-chain precursor. MST1R is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung. It belongs to the MET receptor tyrosine kinase family. MST1R is located on the human chromosome at 3p21.31.

特異性

Anti-MST1R recognizes human MST1R.

免疫原

synthetic peptide corresponding to an internal region of human MST1R, conjugated to KLH. The corresponding sequence is identical in rat and differs by 2 amino acids in mouse.

アプリケーション

Anti-MST1R antibody produced in rabbit may be used in immunoblotting.

生物化学的／生理学的作用

Macrophage-stimulating protein receptor (MST1R) takes part in tumorigenesis. MST1R along with MSP is involved in host defense. Mutation of MST1R is associated with carcinoma of the breast, bladder, lung, colon, prostate, ovary and pancreas. Increased levels of MST1R is observed in aggressive tumors with poor patient survival.

物理的形状

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

保管および安定性

For continuous use, store at 2-8 °C for up to one month. For extended storage, freeze in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.

免責事項

Unless otherwise stated in our catalog, our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable