SAB4200425

Anti-COG1 (N-terminal) antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody

• 別名: Anti-CDG2G, Anti-COG complex subunit 1, Anti-LDLB, Anti-component of oligomeric golgi complex 1, Anti-conserved oligomeric Golgi complex subunit 1, Anti-low density lipoprotein receptor defect B complementing
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: antigen ~110 kDa
• 化学種の反応性: rat, mouse, human
• 濃度: ~1.0 mg/mL
• テクニック: western blot: 2.5-5.0 μg/mL using whole extracts of human HepG2 and rat PC12 cells.
• UniProtアクセッション番号: Q8WTW3
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... COG1(9382) ; mouse ... Cog1(16834) ; rat ... Cog1(303652)

詳細

詳細

The conserved oligomeric Golgi complex 1 (COG1) protein is a member of the conserved oligomeric Golgi (COG) complex. COG complex is an evolutionarily conserved multi-subunit protein complex. COG complex contains eight subunits organized in two heterotrimeric groups, COG-2-COG3-COG4 and COG5-COG6-COG7, which are linked by the dimeric group formed by COG1 and COG8. The COG1 gene is located on the human chromosome at 17q25.1.

特異性

Anti-COG1 (N-terminal) recognizes human and rat COG1.

免疫原

peptide corresponding to the N-terminal region of human COG1, conjugated to KLH. The corresponding sequence is identical in mouse, rat, monkey and bovine COG1.

アプリケーション

Anti-COG1 (N-terminal) antibody produced in rabbit may be used in immunoblotting.

生物化学的／生理学的作用

The conserved oligomeric Golgi complex 1 (COG1) protein is needed for normal Golgi function. It is required for steps in the normal medial and trans-Golgi-associated processing of glycoconjugates. It also plays a role in the organization of the Golgi-localized complex. In humans, mutations in the COG subunit cause novel types of congenital disorders of glycosylation.

物理的形状

solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

保管および安定性

For continuous use, store at 2-8 °C for up to one month. For extended storage freeze in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.

免責事項

Unless otherwise stated in our catalog, our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable