SAB4200343

Anti-MLL2 antibody, Mouse monoclonal

clone MLL2-A, purified from hybridoma cell culture

• 別名: Monoclonal Anti-MLL2 antibody produced in mouse, Anti-AAD10, Anti-ALL1-related protein, Anti-ALR, Anti-CAGL114, Anti-Histone-lysine N-methyltransferase, Anti-KMS, Anti-KMT2B, Anti-KMT2D, Anti-Kabuki make-up syndrome, Anti-Kabuki mental retardation syndrome, Anti-MLL4, Anti-Myeloid/lymphoid or mixed-lineage leukemia 2, Anti-TNRC21
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: mouse
• 結合体: unconjugated
• 抗体製品の状態: purified from hybridoma cell culture
• 抗体製品タイプ: primary antibodies
• クローン: MLL2-A, monoclonal
• 形状: buffered aqueous solution
• 分子量: antigen ~17 kDa
• 化学種の反応性: human
• 濃度: ~1.0 mg/mL
• テクニック: indirect immunofluorescence: suitable; western blot: 0.2-0.5 μg/mL using using human MLL2 partial fusion protein (immunogen)
• アイソタイプ: IgG1
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... MLL2(8085)

詳細

詳細

Myeloid/lymphoid or mixed-lineage leukemia 2 (MLL2) belongs to the SET family of proteins. The SET domain of MLL2 confers strong histone 3 lysine 4 methyltransferase activity. MLL2 is part of a large protein complex called activating signal cointegrator-2 complex (ASCOM).

免疫原

Fusion protein corresponding to the C-terminus of human MLL2. The corresponding sequence is identical in mouse and rat MLL2 and shares 85% homology with MLL3.

アプリケーション

Monoclonal Anti-MLL2 antibody produced in mouse has been used in immunoblotting and immunofluorescence.

生物化学的／生理学的作用

MLL2 acts as an epigenetic transcriptional activator during growth and development. It functions as a transcriptional regulator of the beta-globin and estrogen receptor genes. Mutations in this gene are linked to Kabuki syndrome.

物理的形状

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable