SAB4100235

Monoclonal Anti-SAMHD1 antibody produced in mouse

clone SAMHD1-A200, culture supernatant

• 別名: AntiAGS5, AntiDCIP, AntiHD domain containing 1, AntiHDDC1, AntiMOP-5, AntiOTTHUMP00000030889, AntiSAM domain and HD domain 1, AntiSAM domain- and HD domain-containing protein 1, AntiSBBI88
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: mouse
• 結合体: unconjugated
• 抗体製品の状態: culture supernatant
• 抗体製品タイプ: primary antibodies
• クローン: SAMHD1-A200, monoclonal
• フォーム: aqueous solution
• 分子量: antigen predicted mol wt 72 kDa
• 交差性: human
• テクニック: western blot: suitable
• アイソタイプ: IgG1
• UniProtアクセッション番号: Q9Y3Z3
• 輸送温度: dry ice
• 保管温度: −20°C
• 遺伝子情報: human ... SAMHD1(25939)

詳細

詳細

SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 (SAMHD1) is a deoxynucleoside triphosphate triphosphohydrolase with sterile alpha motif (SAM) and a dGTP-regulated dNTP hydrolase domain (HD). SAMHD1 gene is mapped to human chromosome 20q11.23.

免疫原

SAMHD1 purified recombinant protein

生物化学的／生理学的作用

SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 (SAMHD1) is a key enzyme, which controls the levels of dinucleotide triphosphates. It also acts as an immune response factor cum restriction factor for many virues including the human immunodeficiency virus (HIV) hepatitis B virus (HBV) and herpes simplex virus 1 (HSV-1). SAMHD1 interferon-stimulated gene (ISG) also regulates the human cytomegalovirus and papillomavirus life cycles. Mutation in the SAMHD1 leads to imbalance in dinucleotide levels and is implicated in Aicardi‐Goutières syndrome (AGS) Mutation in SAMHD1 along with Three Prime Repair Exonuclease 1 (TREX1) and Stimulator of interferon genes (STING) genes is also correlated to familial chilblain lupus (FCL).

物理的形状

ダルベッコ変法イーグル培養液（10％ウシ胎児血清、15 mM アジ化ナトリウム含有）

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable