SAB3500457

Anti-TEM4 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 別名: Anti-ARHGEF17, Anti-P164RHOGEF, Anti-Rho guanine nucleotide exchange factor 17, Anti-Tumor endothelial marker 4
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: predicted mol wt 220 kDa
• 化学種の反応性: human
• テクニック: immunofluorescence: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• NCBIアクセッション番号: Q96PE2
• UniProtアクセッション番号: Q96PE2
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... ARHGEF17(9828)

詳細

詳細

Rho guanine nucleotide exchange factor 17 (ARHGEF17), also known as tumor endothelial marker 4 (TEM4) and p164-RhoGEF (Rho-specific guanine-nucleotide exchange factor), encodes a guanine nucleotide exchange factor (GEF) for RhoA GTPases. The encoded protein consists of 1510 amino acids and contains a RhoGEF-specific Dbl homology (DH) domain. It does not contain the typical pleckstrin homology domain. TEM4 is predominantly expressed in the heart. Overexpression of this protein inhibits the transcription of M3 muscarinic receptor-induced genes. TEM4 modulates endothelial cell migration.

免疫原

TEM4 antibody was raised against a 18 amino acid peptide near the center of human TEM4.

特徴および利点

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関連事項

The action of this antibody can be blocked using blocking peptide SBP3500457.

物理的形状

PBS（0.02％ アジ化ナトリウム含有）

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable