SAB3500318

抗TMEM16A抗体 ウサギ宿主抗体

affinity isolated antibody, buffered aqueous solution

• 別名: Anti-Ano1, Anti-Anoctamin 1, Anti-Calcium activated chloride channel, Anti-DOG1, Anti-TAOS1
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 化学種の反応性: mouse, human
• テクニック: indirect ELISA: suitable; western blot: suitable
• NCBIアクセッション番号: NP_060513
• UniProtアクセッション番号: Q5XXA6
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... ANO1(55107)

詳細

詳細

Transmembrane member 16A (TMEM16A) or Anoctamin1 (Ano1) is a calcium-activated chloride channel. It is expressed in the interstitial cells of Cajal (ICC) in the gastrointestinal tract. The gene encoding this protein is localized on human chromosome 11q13.3.

免疫原

TMEM16A antibody was raised against a 17 amino acid peptide from near the amino terminus of human TMEM16A.

生物化学的／生理学的作用

Transmembrane member 16A (TMEM16A) or Ano1 is crucial for normal electrical slow waves and for the proliferation of interstitial cells of Cajal (ICC). The protein has a role in smooth muscle contraction, salivary secretion and cardiac and neuronal excitability. TMEM16A has been associated with head and neck squamous cell carcinoma and breast cancer.

特徴および利点

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関連事項

The action of this antibody can be blocked using blocking peptide SBP3500318.

物理的形状

PBS（0.02％ アジ化ナトリウム含有）

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable