SAB3500315

Anti-TRIAD3A antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: IgG fraction of antiserum
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 分子量: predicted mol wt 95 kDa
• 交差性: mouse, human
• テクニック: immunofluorescence: suitable; immunohistochemistry: suitable; indirect ELISA: suitable; western blot: suitable
• NCBIアクセッション番号: AAP47174
• UniProtアクセッション番号: Q9NWF9
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... RNF216(54476)

詳細

詳細

Ring finger protein 216 (RNF216) is an E3 ubiquitin ligase. The gene encoding this protein is localized on human chromosome 7p22.3.

免疫原

TRIAD3A antibody was raised against a peptide corresponding to 15 amino acids near the amino-terminus of mouse TRIAD3A.

生物化学的／生理学的作用

Ring finger protein 216 (RNF216) associates with toll-like receptors and aids in their degradation. It also aids in the degradation of receptor interacting protein-1 (RIP-1) kinase and negatively modulates tumor necrosis α receptor signaling. The protein acts as an inhibitor of autophagy in macrophages. Mutations in the RNF216 gene have been associated with Gordon Holmes syndrome.

特徴および利点

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関連事項

The action of this antibody can be blocked using blocking peptide SBP3500315.

物理的形状

PBS（0.02％ アジ化ナトリウム含有）

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 2
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable