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Merck

SAB3500310

Sigma-Aldrich

Anti-IL-23 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

別名:

Anti-IL-27 p28, Anti-Interleukin-27

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About This Item

UNSPSCコード:
12352203
NACRES:
NA.41

由来生物

rabbit

結合体

unconjugated

抗体製品の状態

affinity isolated antibody

抗体製品タイプ

primary antibodies

クローン

polyclonal

形状

buffered aqueous solution

分子量

predicted mol wt 21 kDa

化学種の反応性

human, mouse

テクニック

immunocytochemistry: suitable
indirect ELISA: suitable
western blot: suitable

NCBIアクセッション番号

UniProtアクセッション番号

輸送温度

dry ice

保管温度

−20°C

ターゲットの翻訳後修飾

unmodified

遺伝子情報

human ... IL23A(51561)

関連するカテゴリー

詳細

IL-23 is a pro-inflammatory cytokine. It is mostly synthesized by activated DC (dendritic cells) and macrophages. It is a 20.7 kDa protein that has 189 amino acids. IL-23 is mostly expressed on activated/memory T cells and natural killer (NK) cells. This gene is located on human chromosome 12q13.3.

免疫原

IL-23 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human IL-23.

アプリケーション

Anti-IL-23 antibody has been used in western blotting.

生物化学的/生理学的作用

The IL-23 plays a major role in cutaneous immune-mediated inflammatory diseases like psoriasis, allergic contact dermatitis and atopic dermatitis. It is involved in cellular immunity driving the expansion, stabilization and survival of Th17 cells.

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

関連事項

The action of this antibody can be blocked using blocking peptide SBP3500310.

物理的形状

PBS(0.02% アジ化ナトリウム含有)

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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関連製品

製品番号
詳細
価格

保管分類コード

10 - Combustible liquids

WGK

WGK 2

引火点(°F)

Not applicable

引火点(℃)

Not applicable


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

文書ライブラリにアクセスする

Osmotin Protects H9c2 Cells from Simulated Ischemia-Reperfusion Injury through AdipoR1/PI3K/AKT Signaling Pathway
Liu J, et al.
Frontiers in Physiology (2017)
Expression of IL-23/Th17-related cytokines in basal cell carcinoma and in the response to medical treatments
Pellegrini C, et al.
PLoS ONE (2017)
IL23A (interleukin 23, alpha subunit p19)
Inoue N
Atlas of Genetics and Cytogenetics in Oncology and Haematology (2011)
Jianhua Liu et al.
Frontiers in physiology, 8, 611-611 (2017-10-11)
Objective: This study aimed to investigate the effect of osmotin on myocardial ischemia/reperfusion (I/R), as well as the underlying mechanisms. Methods:In vitro I/R injury model was established on rat cardiac myoblast H9c2 cells by oxygen and glucose deprivation followed by
Zhixia Fan et al.
International journal of clinical and experimental pathology, 13(4), 799-809 (2020-05-02)
Psoriasis is an immune-mediated skin disease with abnormal T cells. Regulatory T cells (Treg) are a kind of cell group with immunosuppressive effects. This study aimed to explore the role of Treg cells in the pathogenesis of psoriasis and its

ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.

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