SAB2702324

Monoclonal Anti-CARD12 antibody produced in mouse

clone GT1387, affinity isolated antibody

• 別名: AIFEC, CARD12, CLAN, CLAN1
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: mouse
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: GT1387, monoclonal
• 形状: buffered aqueous solution
• 分子量: 116kDa
• 化学種の反応性: human
• 濃度: 1mg/mL
• テクニック: western blot: 1:1000-1:10000
• アイソタイプ: IgG2a
• UniProtアクセッション番号: Q9NPP4
• 輸送温度: wet ice
• 保管温度: −20°C
• 遺伝子情報: human ... NLRC4(58484)

詳細

免疫原

Recombinant protein encompassing a sequence within the N-terminus region of human CARD12.

アプリケーション

Suggested starting dilutions are as follows: WB: 1:1000-1:10000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

生物化学的／生理学的作用

In C. elegans, Ced4 binds and activates Ced3, an apoptotic initiator caspase, via caspase-associated recruitment domains (CARDs). Human Ced4 homologs include APAF1 (MIM 602233), NOD1/CARD4 (MIM 605980), and NOD2/CARD15 (MIM 605956). These proteins have at least 1 N-terminal CARD domain followed by a centrally located nucleotide-binding domain (NBD or NACHT) and a C-terminal regulatory domain, found only in mammals, that contains either WD40 repeats or leucine-rich repeats (LRRs). CARD12 is a member of the Ced4 family and can induce apoptosis.[supplied by OMIM]

特徴および利点

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

その他情報

Purification: Affinity purified by Protein A

物理的形状

Phosphate-buffered saline, no preservative added.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 1
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable