SAB1300960

Anti-MEKK3 (center) antibody produced in rabbit

Ig fraction of antiserum, buffered aqueous solution

• 別名: Anti-MAP3K3, Anti-MAPK/ERK kinase kinase 3, Anti-MEK kinase 3, Anti-MEKK 3, Anti-Mitogen-activated protein kinase kinase kinase 3
• UNSPSCコード: 12352203

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: Ig fraction of antiserum
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 交差性: human
• テクニック: immunohistochemistry: 1:50-1:100; indirect ELISA: 1:1000; western blot: 1:100-1:500
• NCBIアクセッション番号: NP_976226
• UniProtアクセッション番号: Q99759
• 輸送温度: dry ice
• 保管温度: −20°C
• 遺伝子情報: human ... MEKK3(4215)

詳細

詳細

MEKK3 directly regulates the stress-activated protein kinase (SAPK) and extracellular signal-regulated protein kinase (ERK) pathways by activating SEK and MEK1/2 respectively; it does not regulate the p38 pathway. In cotransfection assays, it enhances transcription from a nuclear factor kappa-B (NFKB)-dependent reporter gene, consistent with a role in the SAPK pathway.

免疫原

MEKK3 (NP_976226, 241-275)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human MEKK3.

物理的形状

精製済みポリクローナル抗体のPBS溶液（0.09％（W/V）アジ化ナトリウム含有）

安全性情報

• 保管分類コード: 12 - Non Combustible Liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable