SAB1300736

Anti-Phospho-ANTXR1-pY425 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

• 別名: 抗ANTXR1抗体, 抗ATR抗体, 抗炭疽毒素レセプター1抗体, 抗腫瘍内皮細胞マーカー8抗体
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 化学種の反応性: human
• テクニック: dot blot: suitable; indirect ELISA: 1:1000
• NCBIアクセッション番号: NP_115584
• UniProtアクセッション番号: Q9H6X2
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: phosphorylation (pTyr425)
• 遺伝子情報: human ... ANTXR1(84168)

詳細

詳細

ANTXR1 is a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. This protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes.

免疫原

ANTXR1 (NP_115584, 409-442)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y425 of human ANTXR1.

物理的形状

精製済みポリクローナル抗体のPBS溶液（0.09％（W/V）アジ化ナトリウム含有）

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable