SAB1300627

Anti-NCAPH2 (center) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• 別名: Anti-NCAPH2, Anti-Non-SMC condensin II complex, Anti-Subunit H2, kleisin β isoform 2
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 品質水準: 100
• 結合体: unconjugated
• 抗体製品の状態: IgG fraction of antiserum
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• フォーム: buffered aqueous solution
• 交差性: human
• テクニック: indirect ELISA: 1:1000; western blot: 1:100-1:500
• NCBIアクセッション番号: NP_689512
• UniProtアクセッション番号: Q6IBW4
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... NCAPH2(29781)

詳細

詳細

Structural maintenance of chromosomes (SMC) and non-SMC condensin proteins associate into complexes that have been implicated in the process of chromosome condensation. A crucial prerequisite for accurate segregation of replicated sister chromatids is the condensation of the chromosomes into a manageable form prior to metaphase. The condensin I complex consists of two SMC subunits, SMC2 and SMC4, and three non-SMC subunits, CAP-H, CAP-G, and CAP-D2. An alternative complex, the condensin II complex, contains alternate non-SMC subunits, CAP-G2, CAP-H2, and CAP-D3. CAP-H2 is also known as Non-SMC condensin II complex, subunit H2 (NCAPH2) or kleisin beta isoform 2. The three non-SMC subunits in the condensing complexes form a regulatory subcomplex that is required to activate the SMC ATPases and to promote mitosis-specific chromatin binding of the holocomplex. The precise individual functions of each non-SMC protein in activation remain to be determined.

The previously assigned protein identifier Q9BUT3 has beenmerged into Q6IBW4. Full details can be found on the UniProt database.

免疫原

NCAPH2 (NP_689512, )
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the central region of human NCAPH2.

物理的形状

精製済みポリクローナル抗体のPBS溶液（0.09％（W/V）アジ化ナトリウム含有）

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: nwg
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable