R9404

Anti-RhoA antibody produced in rabbit

~2 mg/mL, affinity isolated antibody, buffered aqueous solution

• 別名: Anti-p21 Rho
• MDL番号: MFCD09265373
• UNSPSCコード: 12352203
• NACRES: NA.41

特性

• 由来生物: rabbit
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: buffered aqueous solution
• 分子量: antigen ~21 kDa
• 化学種の反応性: monkey, mouse, human
• 濃度: ~2 mg/mL
• テクニック: western blot: 1-2 μg/mL using HEK293 cells expressing human RhoA/ Hela cell extract
• UniProtアクセッション番号: P61586
• 輸送温度: dry ice
• 保管温度: −20°C
• ターゲットの翻訳後修飾: unmodified
• 遺伝子情報: human ... RHOA(387)

詳細

詳細

RhoA (ras homolog family member A) belongs to the Rho GTPase family of proteins. It is located on chromosome 3p21.31.

特異性

Anti-RhoA recognizes human RhoA.

免疫原

synthetic peptide corresponding to amino acids 177-189 located near the C-terminus of human RhoA.

生物化学的／生理学的作用

In multiciliated epithelial cells, RhoA (ras homolog family member A) controls the actin network dynamics. It also modulates membrane protrusion and contractility in the cell body. It is one of the essential factor for Ras transformation. It is associated with cancer metastasis.

物理的形状

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

保管および安定性

For extended storage, freeze in working aliquots at –20 °C. Repeated freezing and thawing, or storage in "frost-free" freezer, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours. For continuous use, store at 2-8°C for up to one month.

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類コード: 10 - Combustible liquids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)