N6909

ニュールツリン ヒト

>95% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder

• 別名: NRT, NTN
• MDL番号: MFCD01867712
• UNSPSCコード: 51111800

特性

• 由来生物: human
• リコンビナント: expressed in E. coli
• アッセイ: >95% (SDS-PAGE)
• 形状: lyophilized powder
• 有効性: 15-50 ng/mL ED₅₀
• 分子量: monomer calculated mol wt ~12.5 kDa; predicted mol wt ~14 kDa by SDS-PAGE (reducing)
• 保管条件: avoid repeated freeze/thaw cycles (Do not store in a frost-free freezer.)
• 不純物: endotoxin, tested
• UniProtアクセッション番号: Q99748
• 保管温度: −20°C
• 遺伝子情報: human ... NRTN(4902)

詳細

生物化学的／生理学的作用

Member of the glial cell line-derived neurotrophic factor family of ligands. Exerts potent effects on the function and survival of central and peripheral neurons. Activates the RET receptor tyrosine kinase, MAP kinase, and phosphatidylinositol 3-kinase pathways. Human and mouse NTN share 91% sequence identity.

物理的形状

Lyophilized from a 0.2 μm filtered solution in 30% acetonitrile and 0.1% TFA containing 1.25 mg bovine serum albumin.

アナリシスノート

The biological activity is measured by its ability to bind recombinant human GFRα2/Fc.

安全性情報

• 保管分類コード: 13 - Non Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)