M3316

Myoseverin B

≥97% (HPLC)

• 別名: 2,6-Bis(4-methoxybenzylamino)-9-cyclohexylpurine
• 実験式（ヒル表記法）: C₂₇H₃₂N₆O₂
• CAS番号: 361431-27-8
• 分子量: 472.58
• MDL番号: MFCD08276922
• UNSPSCコード: 12352200
• PubChem Substance ID: 24724538
• NACRES: NA.77

特性

• アッセイ: ≥97% (HPLC)
• 溶解性: DMSO: soluble; H₂O: insoluble
• 輸送温度: dry ice
• 保管温度: −20°C
• SMILES記法: COc1ccc(CNc2nc(NCc3ccc(OC)cc3)c4ncn(C5CCCCC5)c4n2)cc1
• InChI: 1S/C27H32N6O2/c1-34-22-12-8-19(9-13-22)16-28-25-24-26(33(18-30-24)21-6-4-3-5-7-21)32-27(31-25)29-17-20-10-14-23(35-2)15-11-20/h8-15,18,21H,3-7,16-17H2,1-2H3,(H2,28,29,31,32)
• InChI Key: ZUZXYJOSNSTJMU-UHFFFAOYSA-N

詳細

生物化学的／生理学的作用

Myoseverin, a new microtubule-binding molecule, acts reversibly on myoblast proliferation without the cytotoxic effects displayed by nonpurine-based microtubule-disrupting molecules, like taxol, vinblastine, nocodazole. Myoseverin can be effectively used for the inhibition of new vessel growth by inhibiting endothelial cell function and differentiation of progenitor cells.

安全性情報

• 保管分類コード: 13 - Non Combustible Solids
• WGK: WGK 3
• 引火点(°F): Not applicable
• 引火点(℃): Not applicable
• 個人用保護具 (PPE): Eyeshields, Gloves, type N95 (US)