由来生物
chicken
結合体
unconjugated
抗体製品の状態
affinity isolated antibody
抗体製品タイプ
primary antibodies
クローン
polyclonal
フォーム
buffered aqueous solution
化学種の反応性
human
メーカー/製品名
Genway 15-288-21230
テクニック
western blot: suitable
NCBIアクセッション番号
UniProtアクセッション番号
輸送温度
wet ice
保管温度
−20°C
ターゲットの翻訳後修飾
unmodified
遺伝子情報
human ... NKAP(79576)
アプリケーション
Anti-NKAP antibody produced in chicken is suitable for western blottinganalysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.
生物化学的/生理学的作用
NF-κ-B-activating protein is a protein encoded by the NKAP gene in humans. It is a novel nuclear regulator of TNF- and IL-1-induced NF-κB activation. NKAP is associated with the histone deacetylase HDAC3 and is found to be a part of DNA-binding complex. It is associated with the Notch corepressor complex. NKAP functions as a transcriptional repressor, acts on Notch target genes and is essential for αβ T cell development. It is also required for T cell maturation and the acquisition of functional competency.
物理的形状
Solution in phosphate buffered saline containing 0.02% sodium azide.
免責事項
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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保管分類コード
10 - Combustible liquids
WGK
WGK 1
引火点(°F)
Not applicable
引火点(℃)
Not applicable
個人用保護具 (PPE)
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
Jan Code
GW21230-BULK:
GW21230-50UG:
GW21230-VAR:
最新バージョンのいずれかを選択してください:
Genes to cells : devoted to molecular & cellular mechanisms, 26(3), 180-189 (2021-02-03)
TRA98 is a rat monoclonal antibody (mAb) which recognizes a specific antigen in the nuclei of germ cells. mAb TRA98 has been used to understand the mechanism of germ cell development and differentiation in many studies. In mice, the antigen
Immunity, 30(5), 696-707 (2009-05-05)
T cell development depends on the coordinated interplay between receptor signaling and transcriptional regulation. Through a genetic complementation screen a transcriptional repressor, NKAP, was identified. NKAP associated with the histone deacetylase HDAC3 and was shown to be part of a
Biochemical and biophysical research communications, 310(3), 720-724 (2003-10-11)
Receptor-interacting protein (RIP) is a serine/threonine protein kinase that is critically involved in tumor necrosis factor receptor-1 (TNF-R1)-induced NF-kappaB activation. In a yeast two-hybrid screening for potential RIP-interacting proteins, we identified a novel protein designated as NKAP. Although NKAP interacts
The Journal of experimental medicine, 208(6), 1291-1304 (2011-06-01)
Newly generated T cells are unable to respond to antigen/MHC. Rather, post-selection single-positive thymocytes must undergo T cell maturation to gain functional competency and enter the long-lived naive peripheral T cell pool. This process is poorly understood, as no gene
ライフサイエンス、有機合成、材料科学、クロマトグラフィー、分析など、あらゆる分野の研究に経験のあるメンバーがおります。.
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