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Merck

E7880

Sigma-Aldrich

Eledoisin

≥97% (HPLC)

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About This Item

実験式(ヒル表記法):
C54H85N13O15S
CAS番号:
分子量:
1188.40
MDL番号:
UNSPSCコード:
12352200

アッセイ

≥97% (HPLC)

保管温度

−20°C

SMILES記法

CCC(C)C(NC(=O)C(Cc1ccccc1)NC(=O)C(C)NC(=O)C(CC(O)=O)NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)C2CCCN2C(=O)C3CCC(=O)N3)C(=O)NCC(=O)NC(CC(C)C)C(=O)NC(CCSC)C(N)=O

Amino Acid Sequence

pGlu-Pro-Ser-Lys-Asp-Ala-Phe-Ile-Gly-Leu-Met-NH2

生物化学的/生理学的作用

Tachykinin originally isolated from the salivary gland of octopus with structural homology to substance P; potent vasodilator and hypotensive agent; induces salivation and increases capillary permeability. Agonist at tachykinin NK-2/NK-3 receptors.

保管分類コード

13 - Non Combustible Solids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable

個人用保護具 (PPE)

Eyeshields, Gloves, type N95 (US)


試験成績書(COA)

製品のロット番号・バッチ番号を入力して、試験成績書(COA) を検索できます。ロット番号・バッチ番号は、製品ラベルに「Lot」または「Batch」に続いて記載されています。

以前この製品を購入いただいたことがある場合

文書ライブラリで、最近購入した製品の文書を検索できます。

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P Björup et al.
Bioorganic & medicinal chemistry, 6(7), 891-901 (1998-09-08)
The influence of different reaction systems on alpha-chymotrypsin-catalyzed synthesis of eledoisin and LH-RH peptides from (7 + 4) and (5 + 5) fragments was investigated. The peptide yield was determined in the following systems: buffered aqueous media, frozen solutions, organic
R J Lukas et al.
Neurochemical research, 21(10), 1245-1257 (1996-10-01)
Nicotinic acetylcholine receptors (nAChR) are diverse members of the ligand-gated ion channel superfamily of neurotransmitter receptors and play critical roles in chemical signaling throughout the nervous system. Reports of effects of substance P (SP) on nAChR function prompted us to
C Lippe et al.
Peptides, 19(8), 1435-1438 (1998-11-11)
The tachykinin-dependent stimulation of ion transport across frog skin was studied. Tachykinin stimulation was due to interaction with an NK1-like receptor as [Sar9-Met(O2)11]-Substance P (a very selective NK1 agonist) strongly stimulated SCC, whereas [beta-Ala8]-Neurokinin A 4-10 (a very selective NK2
M Bergstrom et al.
Scandinavian journal of clinical and laboratory investigation, 55(8), 679-689 (1995-12-01)
Tachykinins are a family of peptides that may be present in and secreted from carcinoid tumours of mid-gut origin. They are likely to play a role in the pathogenesis of, e.g. the flush, dyspnoea and valvular heart disease seen in
G Hölzemann et al.
International journal of peptide and protein research, 44(2), 105-111 (1994-08-01)
The synthesis of 11 cyclic hexapeptides, some of which contain a carbohydrate side chain moiety, is described in this paper. A glycosylamine was coupled without hydroxyl protecting groups either directly or via a butyric acid spacer to the side chain

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