E0907

抗リン酸化-上皮成長因子受容体 (pTyr⁸⁴⁵) ウサギ宿主抗体

affinity isolated antibody, lyophilized powder

• 別名: 抗EGFR, リン酸化型(pTyr⁸⁴⁵)抗体
• UNSPSC Code: 51111800
• MDL number: MFCD03845329
• Conjugate: unconjugated
• Clone: polyclonal
• Application: FACS, IHC, WB
• Citations: 3

特性

• biological source: rabbit
• Quality Segment: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: lyophilized powder
• species reactivity: human
• technique(s): flow cytometry: 5 μg/mL, immunohistochemistry: 15 μg/mL, western blot: 0.5 μg/mL
• UniProt accession no.: P00533
• storage temp.: −20°C
• Gene Information: human ... EGFR(1956)

詳細

Immunogen

purified, synthetic phosphopeptide corresponding to residues surrounding tyrosine 845 of human epidermal growth factor receptor.

Biochem/physiol Actions

EGFR is a transmembrane glycoprotein that binds to the EGF family. It is a pivotal regulator of cell proliferation, growth, differentiation and DNA repair after radiation-induced damage. Mutations in the gene encoding EGFR are associated with a number of malignancies including lung cancer and colorectal cancer. Phosphorylation of Tyr845 is associated with EGFR mutation and serves as a surrogate marker.

Physical form

凍結乾燥品(PBS溶液, 5%トレハロース含有, 0.2 μmフィルター滅菌済み)。

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全性情報

• 保管分類: 13 - Non Combustible Solids
• 一体何が起きているの？: WGK 1
• 引火点 (F): Not applicable
• 引火点（°C）: Not applicable
• PPE（個人用保護具）: Eyeshields, Gloves, type N95 (US)