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D0770

Sigma-Aldrich

2′-Deoxyguanylyl(3′→5′)-2′-deoxyguanosine sodium salt

≥98%

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About This Item

化学式:
C20H24N10O10PNa
CAS番号:
113753-10-9
分子量:
618.43
MDL番号:
MFCD00058555
UNSPSCコード:
41106305
PubChem Substance ID:
24893293

アッセイ

≥98%

保管温度

−20°C

SMILES記法

[Na].NC1=NC(=O)c2ncn(C3CC(O)C(COP(O)(=O)OC4CC(OC4CO)n5cnc6C(=O)N=C(N)Nc56)O3)c2N1

アプリケーション

2′-Deoxyguanylyl(3γ→5γ)-2′-deoxyguanosine is a dinucleotide d(GpG) construct used in conjunction with other di- tri- and other oligonucleotides as a model compounds to study the physiochemical interactions of various metal ions and other compounds with DNA structure.

保管分類コード

13 - Non Combustible Solids

WGK

WGK 3

引火点(°F)

Not applicable

引火点(℃)

Not applicable

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試験成績書（COA）

Lot/Batch Number
012K18554
047H0727
047H07271
046H0495
039H11762

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Elizabeth F Day et al.
Rapid communications in mass spectrometry : RCM, 21(6), 903-910 (2007-02-23)
Dirhenium adducts of purine dinucleotides were identified by mass spectrometry. In consecutive studies, Re(2)(O(2)C(2)H(3))(2)Cl(4) . 2H(2)O was reacted with 2'-deoxyguanylyl(3'-->5')-2'-deoxyguanosine (dGpG) and 2'-deoxyadenylyl(3'-->5')-2'-deoxyguanosine (dApG) in H(2)O or D(2)O. These reactions were monitored to identify novel dinuclear rhenium:dinucleotide complexes as confirmed
Electron attachment to hydrated oligonucleotide dimers: guanylyl-3′,5′-cytidine and cytidylyl-3′,5′-guanosine.
Gu J, Xie Y, Schaefer HF 3rd.
Chemistry (Easton), 16, 5089-5096 (2010)
Carla P Da Costa et al.
Inorganic chemistry, 42(11), 3475-3482 (2003-05-28)
The acidity constants of guanylyl(3'-->5')guanosine (GpG(-)) and 2'-deoxyguanylyl(3'-->5')-2'-deoxyguanosine [d(GpG)(-)] for the deprotonation of their (N1)H sites were measured by potentiometric pH titrations in aqueous solution (25 degrees C; I = 0.1 M, NaNO(3)). The same method was used for the
Bernd Knobloch et al.
Organic & biomolecular chemistry, 4(6), 1085-1090 (2006-03-10)
The dinucleotide d(pGpG) is an often employed DNA model to study various kinds of interactions between DNA and metal ions, but its acid-base properties were not yet described in detail. In this study the six deprotonation reactions of H4[d(pGpG)]+ are

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