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| あなたへ/カタログ番号 | 在庫状況 | 単価 |
|---|---|---|
50 μg | カートの在庫状況を確認する | ¥101,000 |
この商品について
UNSPSC Code:
12352202
NACRES:
NA.77
¥101,000
カートの在庫状況を確認する
製品名
Cystatin B human, recombinant, expressed in E. coli
recombinant
expressed in E. coli
Quality Segment
description
contains a N-terminal 7X His-tag
assay
≥95% (SDS-PAGE)
form
solid
mol wt
apparent mol wt ~13 kDa by SDS-PAGE (reducing)
NCBI accession no.
storage temp.
−20°C
Gene Information
human ... CSTB(1476)
General description
Cystatin B is a member of the type 1 (stefins) superfamily of cystatins. Cystatin B is encoded by the CSTB gene and functions as an intracellular thiol protease inhibitor regulating the activity of members of the papain family and cathepsins B, H, and L. Cystatin B may also protect cellular components from the effects of proteases that leak from lysosomes. Mutations in the CSTB gene are thought to be the primary defect in patients with Progressive Myoclonus Epilepsy (EPM1).
Application
Suitable for use as a cysteine-protease inhibitor. Is tested for suitability as an inhibitor of the enzymatic activity of papain.
Biochem/physiol Actions
Cystatin B was shown to interact with the protein RACK-1, β-spectrin and neurofilament light chain NF-L forming a unique multiprotein complex specifically in the cerebellum, confirming its function in the brain. [1]
Preparation Note
Cystatin B should be reconstituted at 100 μg/mL in steile 25 mM Tris pH 7.5 and 100 mM NaCl. Reconstituted product should be stored in single-use aliquots at -70° C and should be stable for at least 3 months.
1 of 1
当該品目 | |||
|---|---|---|---|
| assay ≥95% (SDS-PAGE) | assay - | assay ≥95% (SDS-PAGE) | assay ≥95% (SDS-PAGE) |
| Gene Information human ... CSTB(1476) | Gene Information human ... CSTB(1476) | Gene Information human ... CST3(1471) | Gene Information human ... CTSB(1508) |
| Quality Level 200 | Quality Level 100 | Quality Level 200 | Quality Level 100 |
| form solid | form buffered aqueous solution | form lyophilized powder | form liquid |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. −70°C |
| mol wt apparent mol wt ~13 kDa by SDS-PAGE (reducing) | mol wt - | mol wt - | mol wt - |
保管分類
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
適用法令
試験研究用途を考慮した関連法令を主に挙げております。化学物質以外については、一部の情報のみ提供しています。 製品を安全かつ合法的に使用することは、使用者の義務です。最新情報により修正される場合があります。WEBの反映には時間を要することがあるため、適宜SDSをご参照ください。
C4249-50UG-PW: + C4249-BULK: + C4249-VAR: + C4249-50UG:
jan



