B9928

Anti-Bone Morphogenetic Protein Receptor 2 antibody produced in goat

affinity isolated antibody, lyophilized powder

• 別名: Anti-BMP R2
• MDL番号: MFCD02095904
• UNSPSCコード: 51111800

特性

• 由来生物: goat
• 結合体: unconjugated
• 抗体製品の状態: affinity isolated antibody
• 抗体製品タイプ: primary antibodies
• クローン: polyclonal
• 形状: lyophilized powder
• 化学種の反応性: human
• テクニック: indirect ELISA: 0.5-1.0 μg/mL; western blot: 0.1-0.2 μg/mL
• UniProtアクセッション番号: Q13873
• 保管温度: −20°C
• 遺伝子情報: human ... BMPR2(659)

詳細

詳細

Bone morphogenetic proteins (BMPs) are the members of the TGF-β superfamily and are identified as the critical factors for formation of bone and cartilage, hematopoietic cell formation and mesoderm patterning. Apart from this BMPs have immune regulatory functions. The cellular effects of BMPs are mediated by a heteromeric complex composed of type I and type II receptors. Bone Morphogenetic Protein Receptor 2 (BMP R2) is a 70-80kD protein that belongs to serine/threonine kinases family. BMPs bind to BMP R2 and then recruits the transducing type I receptor which in turn activate the Smad protein signaling pathway. Anti-Bone Morphogenetic Protein Receptor 2 (BMP R2) antibody can be used in western blotting (working concentration:- 0.1-0.2 μg/mL). Goat anti-BMP R2 antibody reacts specifically with recombinant human BMP-R2. The antibody exhibits 10% (approx.) cross-reactivity with recombinant mouse BMP-RIB using reducing conditions and less than 1% cross-reactivity with recombinant mouse BMP-RIA and recombinant human BMP-RIA.

特異性

ウェスタンブロット(還元条件)における交差性は、リコンビナントマウスBMP RIBと10%、リコンビナントヒトおよびマウスBMP RIAと<1%です。

免疫原

NSO細胞で発現させたリコンビナントヒトBMP R2。

アプリケーション

Anti-Bone Morphogenetic Protein Receptor 2 (BMP R2) antibody may be used in indirect ELISA at a working antibody concentration of 0.5-1.0 μg/ml.

物理的形状

凍結乾燥品(PBS溶液, 5%トレハロ-ス含有)。

免責事項

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.